COVID-19 convalescent plasma and clinical trials: understanding conflicting outcomes

D Focosi, M Franchini, L Pirofski… - Clinical microbiology …, 2022 - Am Soc Microbiol
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …

Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning

K Röltgen, SD Boyd - Annual Review of Pathology: Mechanisms …, 2024 - annualreviews.org
As the COVID-19 pandemic has evolved during the past years, interactions between human
immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …

Guidance on the use of convalescent plasma to treat immunocompromised patients with coronavirus disease 2019

EM Bloch, D Focosi, S Shoham… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) is a safe and
effective treatment for COVID-19 in immunocompromised (IC) patients. IC patients have a …

Overview of autoantibodies in COVID‐19 convalescents

K Dobrowolska, D Zarębska‐Michaluk… - Journal of medical …, 2023 - Wiley Online Library
Accumulating evidence shows that SARS‐CoV‐2 can potentially trigger autoimmune
processes, which can be responsible for the long‐term consequences of COVID‐19 …

[HTML][HTML] Rates among hospitalized patients with COVID-19 treated with convalescent plasma: a systematic review and meta-analysis

JW Senefeld, EK Gorman, PW Johnson, ME Moir… - … : Innovations, Quality & …, 2023 - Elsevier
Objective To examine the association of COVID-19 convalescent plasma transfusion with
mortality and the differences between subgroups in hospitalized patients with COVID-19 …

Estimates of actual and potential lives saved in the United States from the use of COVID-19 convalescent plasma

Q Dragotakes, PW Johnson, MR Buras… - Proceedings of the …, 2024 - pnas.org
In the Spring of 2020, the United States of America (USA) deployed COVID-19 convalescent
plasma (CCP) to treat hospitalized patients. Over 500,000 patients were treated with CCP …

Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response

M Marconato, IA Abela, A Hauser… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND Neutralizing antibodies are considered a key correlate of protection by
current SARS-CoV-2 vaccines. The manner in which human infections respond to …

Convalescent plasma therapy in COVID-19: Unravelling the data using the principles of antibody therapy

A Casadevall, MJ Joyner, LA Pirofski… - Expert review of …, 2023 - Taylor & Francis
Introduction When the COVID-19 pandemic struck no specific therapies were available and
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …

Vaccine-boosted convalescent plasma therapy for patients with immunosuppression and COVID-19

JG Ripoll, EK Gorman, JE Juskewitch… - Blood …, 2022 - ashpublications.org
Although severe coronavirus disease 2019 (COVID-19) and death from COVID-19 are
generally preventable in immunocompetent people in areas of the world with sufficient …

Impact of the COVID‐19 pandemic on blood donation and transfusions in the United States in 2020

SV Basavaraju, RJ Free, JL Chavez Ortiz… - …, 2023 - Wiley Online Library
Introduction Reports have suggested the COVID‐19 pandemic resulted in blood donation
shortages and adverse impacts on the blood supply. Using data from the National Blood …