Breast cancer: Biology, biomarkers, and treatments
During the past recent years, various therapies emerged in the era of breast cancer. Breast
cancer is a heterogeneous disease in which genetic and environmental factors are involved …
cancer is a heterogeneous disease in which genetic and environmental factors are involved …
Prognostic and predictive biomarkers in breast cancer: Past, present and future
Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …
management are the determination of prognosis and identification of the most appropriate …
The 2018 biomembrane curvature and remodeling roadmap
P Bassereau, R Jin, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …
recognized for many years and has fascinated scientists from a wide range of different …
[HTML][HTML] Breast cancer: molecular mechanisms of underlying resistance and therapeutic approaches
Breast cancer (BC) affects over 250,000 women in the US each year. Drug-resistant cancer
cells are responsible for most breast cancer fatalities. Scientists are developing novel …
cells are responsible for most breast cancer fatalities. Scientists are developing novel …
Biointerface engineering with nucleic acid materials for biosensing applications
S Shi, J Chen, X Wang, M Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Molecular recognition at the biointerface plays a critical role in sensing molecular
interactions (eg, DNA hybridization) and extracellular changes, which can directly affect the …
interactions (eg, DNA hybridization) and extracellular changes, which can directly affect the …
Biomarkers in breast cancer: an old story with a new end
L Neves Rebello Alves, D Dummer Meira… - Genes, 2023 - mdpi.com
Breast cancer is the second most frequent cancer in the world. It is a heterogeneous disease
and the leading cause of cancer mortality in women. Advances in molecular technologies …
and the leading cause of cancer mortality in women. Advances in molecular technologies …
Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy
Human epidermal growth factor receptor 2 (HER2) gene amplification and/or protein
overexpression in tumors is a prerequisite for initiation of trastuzumab therapy. Although …
overexpression in tumors is a prerequisite for initiation of trastuzumab therapy. Although …
[HTML][HTML] Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels
As described in the literature the interaction between cholesterol and membrane proteins
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …
Cholesterol- and actin-centered view of the plasma membrane: updating the Singer–Nicolson fluid mosaic model to commemorate its 50th anniversary†
A Kusumi, TA Tsunoyama, B Tang… - Molecular Biology of …, 2023 - Am Soc Cell Biol
Two very polarized views exist for understanding the cellular plasma membrane (PM). For
some, it is the simple fluid described by the original Singer–Nicolson fluid mosaic model. For …
some, it is the simple fluid described by the original Singer–Nicolson fluid mosaic model. For …
Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression
H Asperger, N Stamm, B Gierke, M Pawlak… - Breast Cancer …, 2020 - Springer
Background PGRMC1 (progesterone receptor membrane component 1) is a highly
conserved heme binding protein, which is overexpressed especially in hormone receptor …
conserved heme binding protein, which is overexpressed especially in hormone receptor …