[HTML][HTML] Organ-organ communication: The liver's perspective

F Wang, KF So, J Xiao, H Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Communication between organs participates in most physiological and pathological events.
Owing to the importance of precise coordination among the liver and virtually all organs in …

Peroxisomal stress response and inter-organelle communication in cellular homeostasis and aging

J Kim, H Bai - Antioxidants, 2022 - mdpi.com
Peroxisomes are key regulators of cellular and metabolic homeostasis. These organelles
play important roles in redox metabolism, the oxidation of very-long-chain fatty acids …

Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression

S Wang, L Zhou, N Ji, C Sun, L Sun, J Sun, Y Du… - Drug Resistance …, 2023 - Elsevier
Abstract Acylphosphatase 1 (ACYP1), a protein located in the mammalian cell cytoplasm,
has been shown to be associated with tumor initiation and progression by functioning as a …

Social isolation shortens lifespan through oxidative stress in ants

A Koto, M Tamura, PS Wong, S Aburatani… - Nature …, 2023 - nature.com
Social isolation negatively affects health, induces detrimental behaviors, and shortens
lifespan in social species. Little is known about the mechanisms underpinning these effects …

Spiky cascade biocatalysts as peroxisome-mimics for ultrasound-augmented tumor ablation

H Yuan, L Zhang, T Ma, J Huang, C Nie… - … Applied Materials & …, 2022 - ACS Publications
Ultrasound (US)-augmented tumor ablation with sono-catalysts has emerged as a promising
therapeutic modality due to high tissue penetration, nonionizing performance, and low cost …

Coordination of tumor growth and host wasting by tumor-derived Upd3

G Ding, X Xiang, Y Hu, G Xiao, Y Chen, R Binari… - Cell reports, 2021 - cell.com
Summary yki-induced gut tumors in Drosophila are associated with host wasting, including
muscle dysfunction, lipid loss, and hyperglycemia, a condition reminiscent of human cancer …

Physiological ROS controls Upd3-dependent modeling of ECM to support cardiac function in Drosophila

J Gera, P Budakoti, M Suhag, L Mandal, S Mandal - Science Advances, 2022 - science.org
Despite their highly reactive nature, reactive oxygen species (ROS) at the physiological level
serve as signaling molecules regulating diverse biological processes. While ROS usually …

[HTML][HTML] Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

H Huang, T Wang, L Wang, Y Huang, W Li, Y Hu… - Experimental …, 2023 - Elsevier
Heart disease is a significant health concern for elderly individuals, with heart aging being
the primary cause. Recent studies have shown that autophagy can play a protective role in …

Leptin-and cytokine-like unpaired signaling in Drosophila

M Zandawala, J Gera - Molecular and Cellular Endocrinology, 2024 - Elsevier
Animals have evolved a multitude of signaling pathways that enable them to orchestrate
diverse physiological processes to tightly regulate systemic homeostasis. This signaling is …

Roles of insect oenocytes in physiology and their relevance to human metabolic diseases

K Huang, Y Liu, N Perrimon - Frontiers in insect science, 2022 - frontiersin.org
Oenocytes are large secretory cells present in the abdomen of insects known to synthesize
very-long-chain fatty acids to produce hydrocarbons and pheromones that mediate courtship …