Paramagnetic centers in biomolecules, such as specific metal ions that are bound to a
protein, affect the nuclei in their surrounding in various ways. One of these effects is the …

The neurohormone N-acetyl-5-methoxytryptamine, better known as melatonin, is a
tryptophan derivative with a wide range of biological effects that is present in many …

The production of the pineal hormone melatonin is synchronized with day-night cycle via
multisynaptic pathway including suprachiasmatic nucleus linking several physiological …

The cytoskeleton is a phylogenetically well‐preserved structure that plays a key role in cell
physiology. Dynamic and differential changes in cytoskeletal organization occur in cellular …

Melatonin was discovered more than 60 years ago. Since then, several seminal discoveries
have allowed us to define its function as a neuroendocrine hormone and its molecular …

Melatonin (MEL) is a pleiotropic indolamine that reaches multiple intracellular targets.
Among these, MEL binds to calmodulin (CaM) with high affinity. In presence of Ca2+, CaM …

Phytomelatonin is a small multifunctional molecule found ubiquitously in plants, which plays
an important role in plant growth, development, and biotic and abiotic stress responses. The …

Aging is a complex process associated with a diminished ability to respond to stress, a
progressive increase in free radical generation and a decline in immune function. Melatonin …

It has widely been thought that in the process of nerve regeneration Schwann cells populate
the injury site with myelinating, non–myelinating, phagocytic, repair, and mesenchyme–like …

Physiologic relaxation of vascular smooth muscle is induced by the cyclic guanosine
monophosphate (cGMP)-dependent protein kinase Iα enzyme (cGKIα), which activates …