Recurrent pregnancy loss: current perspectives

H El Hachem, V Crepaux, P May-Panloup… - … journal of women's …, 2017 - Taylor & Francis
Recurrent pregnancy loss is an important reproductive health issue, affecting 2%–5% of
couples. Common established causes include uterine anomalies, antiphospholipid …

Current concepts and new trends in the diagnosis and management of recurrent miscarriage

J Alijotas-Reig, C Garrido-Gimenez - Obstetrical & gynecological …, 2013 - journals.lww.com
Pregnancy is a proinflammatory and hypercoagulable state. Miscarriage concerns
approximately 15% of pregnancies. Recurrent miscarriage is a rather rare condition with an …

Antiphospholipid syndrome in pregnancy: new and old pathogenetic mechanisms

S D'Ippolito, G Barbaro, C Paciullo, C Tersigni… - International journal of …, 2023 - mdpi.com
The antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized,
according to the Sydney criteria, by the persistent presence of autoantibodies directed …

Recurrent miscarriage and thrombophilia: an update

K McNamee, F Dawood… - Current Opinion in …, 2012 - journals.lww.com
The cause of recurrent miscarriage is multifactorial and appropriate treatment continues to
be a challenge. Laboratory tests need to be standardized and well designed multicentre …

Obstetric antiphospholipid syndrome: a recent classification for an old defined disorder

S D'Ippolito, PL Meroni, T Koike, M Veglia… - Autoimmunity …, 2014 - Elsevier
Obstetric antiphospholipid syndrome (APS) is now being recognized as a distinct entity from
vascular APS. Pregnancy morbidity includes> 3 consecutive and spontaneous early …

Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expression

XX Wu, S Guller, JH Rand - American journal of obstetrics and gynecology, 2011 - Elsevier
OBJECTIVE: Antibody-mediated disruption of the annexin A5 anticoagulant shield has been
posited to be a thrombogenic mechanism in the antiphospholipid syndrome. We recently …

Antiphospholipid antibody syndrome

WH Kutteh, CD Hinote - Obstetrics and Gynecology Clinics, 2014 - obgyn.theclinics.com
Antiphospholipid antibodies (aPLs) are acquired antibodies (immunoglobulin [Ig] G, IgM,
and/or IgA isotypes) that react against negatively charged phospholipids. They were …

Aspirin or heparin or both in the treatment of recurrent spontaneous abortion in women with antiphospholipid antibody syndrome: a meta-analysis of randomized …

C Lu, Y Liu, HL Jiang - The Journal of Maternal-Fetal & Neonatal …, 2019 - Taylor & Francis
Objective: This study was designed to evaluate the efficacy of aspirin or heparin or both in
the treatment for recurrent spontaneous abortion (RSA) in women with antiphospholipid …

Prothrombotic mechanisms and anticoagulant therapy in dogs with immune‐mediated hemolytic anemia

L Kidd, N Mackman - … of Veterinary Emergency and Critical Care, 2013 - Wiley Online Library
Objective To review the pathophysiology of thrombosis in hemolytic disease, and the
efficacy of thromboprophylaxis in dogs with immune‐mediated hemolytic anemia (IMHA) …

Obstetric antiphospholipid syndrome: an update on pathophysiology and management

JM Ernest, PB Marshburn… - Seminars in reproductive …, 2011 - thieme-connect.com
Antiphospholipid antibodies (aPLs) are acquired antibodies directed against negatively
charged phospholipids, a group of inner and outer cell membrane antigens found in …