Sedation and analgesia are important components of care for the mechanically ventilated
patient in the intensive care unit (ICU). An understanding of commonly used medications is …

Volatile anesthetic agent use in the intensive care unit, aided by technological advances,
has become more accessible to critical care physicians. With increasing concern over …

Rationale: Sevoflurane improves gas exchange, and reduces alveolar edema and
inflammation in preclinical studies of lung injury, but its therapeutic effects have never been …

As most critically ill or injured patients will require some degree of sedation, the goal of this
paper was to comprehensively review the literature associated with use of sedative agents …

Inhaled sedation with halogenated agents, such as isoflurane or sevoflurane, is now
feasible in intensive care unit (ICU) patients through dedicated vaporisers and scavenging …

Inhaled sedation was recently approved in Europe as an alternative to intravenous sedative
drugs for intensive care unit (ICU) sedation. The aim of this narrative review was to …

Background Isoflurane may be protective in pre-clinical models of lung injury but its use in
patients with lung injury remains controversial and the mechanism of its protective effects …

Background Volatile anesthetics are used more commonly for sedation in the intensive-care-
unit (ICU). However, evidence for long-term use remains low. We therefore conducted a …

There is a shift in critical care to adopt volatile anaesthetics as sedatives for certain patients
using mechanical ventilation. Accompanying this shift is a growing body of literature …

Currently coronavirus disease 2019 (COVID-19) is holding the world in its grip. Numbers of
infected individuals continue to increase each day and worldwide mortality rate attributable …