The authors provide a comprehensive summary of all randomized, controlled trials (n= 76)
involving the clinical administration of liposomal bupivacaine (Exparel; Pacira …

Background/Importance Liposomal bupivacaine (LB) is a prolonged release formulation of
conventional bupivacaine designed for prolonging local or peripheral regional single …

Background Liposomal bupivacaine is purported to extend analgesia of peripheral nerve
blocks when administered perineurally. However, evidence of the clinical effectiveness of …

Background The opioid crisis has prompted surgeons to search for alternative postoperative
methods of analgesia. Liposomal bupivacaine is a long-acting local anesthetic formulation …

Background: There has been a surge in interest with regard to the utility of liposomal
bupivacaine as part of a perioperative pain management protocol. The current study was …

Background: The analgesic effect of adding liposomal bupivacaine to standard bupivacaine
in supraclavicular brachial plexus block is not known. The authors hypothesized that …

Background: Liposomal bupivacaine (LB) is a long-lasting local anesthetic agent that was
developed for use in the surgical setting to help manage postoperative pain. The objective of …

Abstract Purpose of Review Acute postoperative pain reduction is a major target against the
opioid crisis. While opioids have traditionally been the mainstay for postoperative analgesia …

Background: The aim of this study was to evaluate the use of machine learning to predict
persistent opioid use after hand surgery. Methods: The authors trained 2 algorithms to …

Chronic pain is a debilitating condition that affects millions of patients worldwide,
contributing to a high disease burden and millions of dollars in lost wages, missed …