[HTML][HTML] NMR of RNA-structure and interactions

M Marušič, M Toplishek, J Plavec - Current Opinion in Structural Biology, 2023 - Elsevier
RNA was shown to have a more substantial role in the regulation of diverse cellular
processes than anticipated until recently. Answers to questions what is the structure of …

A riboswitch separated from its ribosome-binding site still regulates translation

GM Schroeder, O Akinyemi, J Malik… - Nucleic Acids …, 2023 - academic.oup.com
Riboswitches regulate downstream gene expression by binding cellular metabolites.
Regulation of translation initiation by riboswitches is posited to occur by metabolite …

Advances in RNA labeling with trifluoromethyl groups

C Eichler, M Himmelstoß, R Plangger… - … A European Journal, 2023 - Wiley Online Library
Fluorine labeling of ribonucleic acids (RNA) in conjunction with 19F NMR spectroscopy has
emerged as a powerful strategy for spectroscopic analysis of RNA structure and dynamics …

Translation regulation by a Guanidine-II riboswitch is highly tunable in sensitivity, dynamic range, and apparent cooperativity

CM Focht, DA Hiller, SG Grunseich, SA Strobel - Rna, 2023 - rnajournal.cshlp.org
Riboswitches function as important translational regulators in bacteria. Comprehensive
mutational analysis of transcriptional riboswitches has been used to probe the energetic …

Shine–Dalgarno Accessibility Governs Ribosome Binding to the Adenine Riboswitch

J Blechar, V de Jesus, B Fürtig… - ACS Chemical …, 2024 - ACS Publications
Translational riboswitches located in the 5′ UTR of the messenger RNA (mRNA) regulate
translation through variation of the accessibility of the ribosome binding site (RBS). These …

[HTML][HTML] Regulatory mechanisms through RNA conformational switching and dynamics

PC Bevilacqua, BS Tolbert - Journal of molecular biology, 2022 - ncbi.nlm.nih.gov
The last few years have deepened our appreciation of RNA as a magical molecule. RNA
serves as an enzyme (ribozyme) and receptor (riboswitch). It is essential for gene editing …