Supportive and symptomatic management of amyotrophic lateral sclerosis

EV Hobson, CJ McDermott - Nature Reviews Neurology, 2016 - nature.com
The main aims in the care of individuals with amyotrophic lateral sclerosis (ALS) are to
minimize morbidity and maximize quality of life. Although no cure exists for ALS, supportive …

Advances in molecular pathology, diagnosis, and treatment of amyotrophic lateral sclerosis

H Ilieva, M Vullaganti, J Kwan - bmj, 2023 - bmj.com
Although the past two decades have produced exciting discoveries in the genetics and
pathology of amyotrophic lateral sclerosis (ALS), progress in developing an effective therapy …

ESPEN guideline clinical nutrition in neurology

R Burgos, I Bretón, E Cereda, JC Desport, R Dziewas… - Clinical Nutrition, 2018 - Elsevier
Neurological diseases are frequently associated with swallowing disorders and malnutrition.
Moreover, patients with neurological diseases are at increased risk of micronutrient …

Impact of expiratory strength training in amyotrophic lateral sclerosis: Results of a randomized, sham‐controlled trial

EK Plowman, L Tabor‐Gray, KM Rosado… - Muscle & …, 2019 - Wiley Online Library
Introduction The purpose of this study was to determine the impact of an in‐home expiratory
muscle strength training (EMST) program on pulmonary, swallow, and cough function in …

Physical therapy for individuals with amyotrophic lateral sclerosis: current insights

VD Bello-Haas - Degenerative neurological and neuromuscular …, 2018 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative, and inevitably fatal
disease. There is no cure for ALS and life expectancy is typically 2–5 years after symptom …

Respiratory involvement in neuromuscular disorders

M Boentert, S Wenninger… - Current opinion in …, 2017 - journals.lww.com
First, it is outlined in which subtypes of NMD respiratory muscle dysfunction is particularly
relevant. Second, new developments regarding diagnostic procedures, including respiratory …

Minimally detectable change and minimal clinically important difference of a decline in sentence intelligibility and speaking rate for individuals with amyotrophic lateral …

KL Stipancic, Y Yunusova, JD Berry, JR Green - Journal of Speech …, 2018 - ASHA
Purpose The purpose of this study was to determine the minimally detectable change (MDC)
and minimal clinically important difference (MCID) of a decline in speech sentence …

Oropharyngeal dysphagia in acute cervical spinal cord injury: a literature review

J McRae, S Morgan, E Wallace, A Miles - Dysphagia, 2023 - Springer
Dysphagia (swallowing impairment) is a frequent complication of cervical spinal cord injury
(cSCI). Recently published national guidance in the UK on rehabilitation after traumatic …

Rehabilitation of airway protection in individuals with movement disorders: A telehealth feasibility study

JS Sevitz, JC Borders, AE Dakin, BR Kiefer… - American journal of …, 2022 - ASHA
Purpose: Airway protective deficits (swallowing and cough) greatly reduce health and quality
of life and are a pervasive consequence of neurodegenerative movement disorders …

Respiratory muscle training in children and adults with neuromuscular disease

IS Silva, R Pedrosa, IG Azevedo… - Cochrane Database …, 2019 - cochranelibrary.com
Background Neuromuscular diseases (NMDs) are a heterogeneous group of diseases
affecting the anterior horn cell of spinal cord, neuromuscular junction, peripheral nerves and …