Flavonoids are promising safe therapy against COVID-19

MM Alzaabi, R Hamdy, NS Ashmawy… - Phytochemistry …, 2022 - Springer
Flavonoids are a class of phenolic natural products, well-identified in traditional and modern
medicines in the treatment of several diseases including viral infection. Flavonoids showed …

Botanical drugs and supplements affecting the immune response in the time of COVID‐19: Implications for research and clinical practice

T Brendler, A Al‐Harrasi, R Bauer… - Phytotherapy …, 2021 - Wiley Online Library
In times of health crisis, including the current COVID‐19 pandemic, the potential benefit of
botanical drugs and supplements emerges as a focus of attention, although controversial …

Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking

P Makvandi, M Chen, R Sartorius, A Zarrabi… - Nano Today, 2021 - Elsevier
Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …

Heparan sulfate proteoglycans in viral infection and treatment: a special focus on SARS-CoV-2

V De Pasquale, MS Quiccione, S Tafuri… - International Journal of …, 2021 - mdpi.com
Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of
unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core …

Secretory vesicles are the principal means of SARS-CoV-2 egress

S Eymieux, R Uzbekov, Y Rouillé, E Blanchard… - Cells, 2021 - mdpi.com
The mechanisms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) egress,
similar to those of other coronaviruses, remain poorly understood. The virus buds in …

Molecular mechanism of the anti-inflammatory action of heparin

L Litov, P Petkov, M Rangelov, N Ilieva… - International Journal of …, 2021 - mdpi.com
Our objective is to reveal the molecular mechanism of the anti-inflammatory action of low-
molecular-weight heparin (LMWH) based on its influence on the activity of two key cytokines …

Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations

SV Giofrè, E Napoli, N Iraci, A Speciale… - Computers in Biology …, 2021 - Elsevier
The outbreak of COVID-19 disease caused by SARS-CoV-2, along with the lack of targeted
medicaments, forced the scientific world to search for new antiviral formulations. In the …

Potential anti-SARS-CoV-2 therapeutics that target the post-entry stages of the viral life cycle: A comprehensive review

RA Al-Horani, S Kar - Viruses, 2020 - mdpi.com
The coronavirus disease-2019 (COVID-19) pandemic continues to challenge health care
systems around the world. Scientists and pharmaceutical companies have promptly …

Brilacidin demonstrates inhibition of SARS-CoV-2 in cell culture

A Bakovic, K Risner, N Bhalla, F Alem, TL Chang… - Viruses, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the newly emergent
causative agent of coronavirus disease-19 (COVID-19), has resulted in more than two …

Antibiotics for the treatment of COVID‐19

Cochrane Haematology Group, M Popp… - Cochrane Database …, 1996 - cochranelibrary.com
Background The effect of antibiotics with potential antiviral and anti‐inflammatory properties
are being investigated in clinical trials as treatment for COVID‐19. The use of antibiotics …