Fully-coupled FSI computational analyses in the ascending thoracic aorta using patient-specific conditions and anisotropic material properties

E Vignali, E Gasparotti, S Celi, S Avril - Frontiers in Physiology, 2021 - frontiersin.org
Computational hemodynamics has become increasingly important within the context of
precision medicine, providing major insight in cardiovascular pathologies. However, finding …

A hybrid mock circulatory loop for fluid dynamic characterization of 3D anatomical phantoms

F Bardi, E Gasparotti, E Vignali… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

Hemodynamics and stresses in numerical simulations of the thoracic aorta: Stochastic sensitivity analysis to inlet flow-rate waveform

A Mariotti, A Boccadifuoco, S Celi, MV Salvetti - Computers & Fluids, 2021 - Elsevier
Numerical simulations of the blood flow inside a patient-specific thoracic aorta in presence
of an aneurysm are considered. We focus on the impact on the numerical predictions of the …

High-versatility left ventricle pump and aortic mock circulatory loop development for patient-specific hemodynamic in vitro analysis

E Vignali, E Gasparotti, A Mariotti, D Haxhiademi… - ASAIO …, 2022 - journals.lww.com
The importance of experimental setups able to reproduce cardiac functions was well
established in the field of clinical innovations. The mock circulatory loops acquired rising …

Fabrication and in-vitro characterization of a polymeric aortic valve for minimally invasive valve replacement

A Cavallo, E Gasparotti, P Losi, I Foffa… - Journal of the …, 2021 - Elsevier
The valve replacement therapy is the standard treatment for severe heart valve diseases.
Nowadays, two types of commercial prosthesis are available: mechanical and biological, but …

A hybrid mock circulatory loop integrated with a LED-PIV system for the investigation of AAA compliant phantoms

F Bardi, E Gasparotti, E Vignali… - … in Bioengineering and …, 2024 - frontiersin.org
Background Cardiovascular diseases remain a leading cause of morbidity and mortality
worldwide and require extensive investigation through in-vitro studies. Mock Circulatory …

Effects of the distribution in space of the velocity-inlet condition in hemodynamic simulations of the thoracic aorta

MN Antonuccio, A Mariotti, S Celi… - … : 8th International Work …, 2020 - Springer
In the present paper the effects of the spatial distribution of the inlet velocity in numerical
simulations of the thoracic aorta have been investigated. First, the results obtained by …

On the Role and Effects of Uncertainties in Cardiovascular in silico Analyses

S Celi, E Vignali, K Capellini… - Frontiers in Medical …, 2021 - frontiersin.org
The assessment of cardiovascular hemodynamics with computational techniques is
establishing its fundamental contribution within the world of modern clinics. Great research …

In Vitro Analysis of Hemodynamics in the Ascending Thoracic Aorta: Sensitivity to the Experimental Setup

A Mariotti, E Vignali, E Gasparotti, M Morello, J Singh… - Applied Sciences, 2023 - mdpi.com
We perform a stochastic sensitivity analysis of the experimental setup of a mock circulatory
loop for in vitro hemodynamics analysis in the ascending thoracic aorta at a patient-specific …

[PDF][PDF] Towards a integrated platform for the investigation of hemodynamics in thoracic aorta: UQ in simulations and experiments

MV Salvetti, A Mariotti, S Celi - PROCEEDINGS OF SIMAI 2020+ 21, 2021 - air.unimi.it
Techniques based on Computational Fluid Dynamics (CFD) have been extensively used in
the last few years to investigate hemodynamics inside arteries in both healthy and diseased …