Rheumatoid arthritis: pathogenic roles of diverse immune cells

S Jang, EJ Kwon, JJ Lee - International journal of molecular sciences, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease associated with
synovial tissue proliferation, pannus formation, cartilage destruction, and systemic …

B cells in rheumatoid arthritis: pathogenic mechanisms and treatment prospects

F Wu, J Gao, J Kang, X Wang, Q Niu, J Liu… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a common, chronic, systemic autoimmune disease, and its
clinical features are the proliferation of joint synovial tissue, the formation of pannus and the …

Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Immunomodulatory effects of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles in rheumatoid arthritis

H Liu, R Li, T Liu, L Yang, G Yin, Q Xie - Frontiers in Immunology, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints and other
organs for which there is currently no effective treatment. Mesenchymal stem cells (MSCs) …

Mesenchymal stem/stromal cells for rheumatoid arthritis treatment: an update on clinical applications

M Lopez-Santalla, R Fernandez-Perez, MI Garin - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects the lining of
the synovial joints leading to stiffness, pain, inflammation, loss of mobility, and erosion of …

Shining the light on clinical application of mesenchymal stem cell therapy in autoimmune diseases

SA Jasim, AV Yumashev, WK Abdelbasset… - Stem Cell Research & …, 2022 - Springer
The autoimmune diseases are associated with the host immune system, chronic
inflammation, and immune reaction against self-antigens, which leads to the injury and …

The immunomodulatory effects of mesenchymal stem cells on regulatory B cells

J Liu, Q Liu, X Chen - Frontiers in Immunology, 2020 - frontiersin.org
The therapeutic potential of mesenchymal stem cells (MSCs) has been investigated in many
preclinical and clinical studies. This potential is dominantly based on the …

Cell-based therapies for rheumatoid arthritis: opportunities and challenges

YJ Li, Z Chen - Therapeutic advances in musculoskeletal …, 2022 - journals.sagepub.com
Rheumatoid arthritis (RA) is the most common immune-mediated inflammatory disease
characterized by chronic synovitis that hardly resolves spontaneously. The current treatment …

JAK inhibitors and modulation of B cell immune responses in rheumatoid arthritis

RA Moura, JE Fonseca - Frontiers in Medicine, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic, systemic immune-mediated inflammatory disease that
can lead to joint destruction, functional disability and substantial comorbidity due to the …

Considerations for novel COVID-19 mucosal vaccine development

W Alturaiki - Vaccines, 2022 - mdpi.com
Mucosal surfaces are the first contact sites of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Most SARS-CoV-2 vaccines induce specific IgG responses …