Copy number variants (CNVs), duplications and deletions of genomic sequences, contribute
to evolutionary adaptation but can also confer deleterious effects and cause disease …

Cellular models such as yeasts are a driving force in biogerontology studies. Their simpler
genome, short lifespans and vast genetic and genomics resources make them ideal to …

Standardized nomenclature for genes, gene products, and isoforms is crucial to prevent
ambiguity and enable clear communication of scientific data, facilitating efficient biocuration …

The unicellular yeast Schizosaccharomyces pombe (fission yeast) retains many of the
splicing features observed in humans and is thus an excellent model to study the basic …

Fungi can cause devastating invasive infections, typically in immunocompromised patients.
Treatment is complicated both by the evolutionary similarity between humans and fungi and …

Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that
do not overlap any coding genes. Some lincRNAs function in various aspects of gene …

Numerous genes required for sexual reproduction remain to be identified even in simple
model species like Schizosaccharomyces pombe. To address this, we developed an assay …

Blake Billmyre uses functional genomics to help understand the biology of fungal
pathogens, with an emphasis on evolution of virulence relevant traits and drug resistance. In …

Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that
do not overlap any coding genes. Some lincRNAs function in various aspects of gene …

Fission yeasts have a unique life history and exhibit distinct evolutionary patterns from other
yeasts. Besides, the species demonstrate stable genome structures despite the relatively …