Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

NMR and metabolomics—A roadmap for the future

DS Wishart, LL Cheng, V Copié, AS Edison… - Metabolites, 2022 - mdpi.com
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**

H de Maissin, PR Groß, O Mohiuddin… - Angewandte Chemie …, 2023 - Wiley Online Library
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Hyperpolarized NMR Spectroscopy: d‐DNP, PHIP, and SABRE Techniques

KV Kovtunov, EV Pokochueva… - Chemistry–An Asian …, 2018 - Wiley Online Library
The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …

Microtesla SABRE enables 10% nitrogen-15 nuclear spin polarization

T Theis, ML Truong, AM Coffey… - Journal of the …, 2015 - ACS Publications
Parahydrogen is demonstrated to efficiently transfer its nuclear spin hyperpolarization to
nitrogen-15 in pyridine and nicotinamide (vitamin B3 amide) by conducting “signal …

Challenges for molecular magnetic resonance imaging

E Terreno, DD Castelli, A Viale, S Aime - Chemical reviews, 2010 - ACS Publications
Challenges for Molecular Magnetic Resonance Imaging | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …

Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research

J Kurhanewicz, DB Vigneron, K Brindle… - Neoplasia, 2011 - Elsevier
A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo
with the goal of improved diagnosis and perhaps therapy. Because of the complexity of …

Facing and overcoming sensitivity challenges in biomolecular NMR spectroscopy

JH Ardenkjaer‐Larsen, GS Boebinger… - Angewandte Chemie …, 2015 - Wiley Online Library
In the Spring of 2013, NMR spectroscopists convened at the Weizmann Institute in Israel to
brainstorm on approaches to improve the sensitivity of NMR experiments, particularly when …