Mechanical properties of single cells: Measurement methods and applications

Y Hao, S Cheng, Y Tanaka, Y Hosokawa… - Biotechnology …, 2020 - Elsevier
Cell mechanical properties, eg elastic and shear modulus, play vital roles in cell activities
and functions, such as cell growth, cell division, cell motion, and cell adhesion …

Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Technologies for measuring red blood cell deformability

K Matthews, ES Lamoureux, ME Myrand-Lapierre… - Lab on a Chip, 2022 - pubs.rsc.org
Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …

Dielectrophoretic manipulation of cancer cells and their electrical characterization

I Turcan, MA Olariu - ACS Combinatorial Science, 2020 - ACS Publications
Electromanipulation and electrical characterization of cancerous cells is becoming a topic of
high interest as the results reported to date demonstrate a good differentiation among …

Microfluidic deformability cytometry: A review

Y Chen, K Guo, L Jiang, S Zhu, Z Ni, N Xiang - Talanta, 2023 - Elsevier
Cell deformability plays an important role in cellular processes and functions, including cell
growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at …

Mechanical fatigue of human red blood cells

Y Qiang, J Liu, M Dao, S Suresh… - Proceedings of the …, 2019 - National Acad Sciences
Fatigue arising from cyclic straining is a key factor in the degradation of properties of
engineered materials and structures. Fatigue can also induce damage and fracture in …

[HTML][HTML] Differential regulation of GUV mechanics via actin network architectures

NH Wubshet, B Wu, S Veerapaneni, AP Liu - Biophysical Journal, 2023 - cell.com
Actin networks polymerize and depolymerize to construct highly organized structures,
thereby endowing the mechanical phenotypes found in a cell. It is generally believed that …

In vitro assay for single-cell characterization of impaired deformability in red blood cells under recurrent episodes of hypoxia

Y Qiang, J Liu, M Dao, E Du - Lab on a Chip, 2021 - pubs.rsc.org
Red blood cells (RBCs) are subjected to recurrent changes in shear stress and oxygen
tension during blood circulation. The cyclic shear stress has been identified as an important …

Simple, cost-effective, and continuous 3D dielectrophoretic microchip for concentration and separation of bioparticles

P Tajik, MS Saidi, N Kashaninejad… - Industrial & …, 2019 - ACS Publications
Dielectrophoresis is a robust approach for manipulating bioparticles in microfluidic devices.
In recent years, many groups have developed dielectrophoresis-based microfluidic systems …

Label-free microfluidics for single-cell analysis

Y Chen, Z Zhou, S Zhu, Z Ni, N Xiang - Microchemical Journal, 2022 - Elsevier
Accurate analysis of the mechanical, electrical, and optical properties of single cells can
provide useful information on their physiological and pathological states. Microfluidics has …