Role of oxidative stress in nanoparticles toxicity

M Horie, Y Tabei - Free radical research, 2021 - Taylor & Francis
Oxidative stress plays a critical role in nanotoxicity. Various types of nanoparticles are
known to induce oxidative stress by generating intracellular reactive oxygen species (ROS) …

Reactive oxygen nano-generators for cancer therapy

D Kalyane, D Choudhary, S Polaka, H Goykar… - Progress in Materials …, 2022 - Elsevier
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …

Ameliorating quercetin constraints in cancer therapy with pH-responsive agarose-polyvinylpyrrolidone-hydroxyapatite nanocomposite encapsulated in double …

A Samadi, M Pourmadadi, F Yazdian, H Rashedi… - International Journal of …, 2021 - Elsevier
Despite quercetin (QC) promising features for cancer therapy, low solubility, poor
permeability, and short biological half-life time significantly confine its application in cancer …

Polymer-bioactive glass composite filaments for 3D scaffold manufacturing by fused deposition modeling: fabrication and characterization

T Distler, N Fournier, A Grünewald, C Polley… - … in bioengineering and …, 2020 - frontiersin.org
Critical size bone defects are regularly treated by auto-and allograft transplantation.
However, such treatments require to harvest bone from patient donor sites, with often limited …

Cobalt nanoparticles for biomedical applications: Facile synthesis, physiochemical characterization, cytotoxicity behavior and biocompatibility

SM Ansari, RD Bhor, KR Pai, D Sen, S Mazumder… - Applied Surface …, 2017 - Elsevier
Abstract Cobalt (Co) nanoparticles (NPs) were produced by a simple, one step hydrothermal
method with the capping of oleic acid. Intrinsic structural, physiochemical and magnetic …

Osteoconductive and electroactive carbon nanofibers/hydroxyapatite nanocomposite tailored for bone tissue engineering: in vitro and in vivo studies

H Samadian, H Mobasheri, M Azami, R Faridi-Majidi - Scientific reports, 2020 - nature.com
In this study, we aimed to fabricate osteoconductive electrospun carbon nanofibers (CNFs)
decorated with hydroxyapatite (HA) crystal to be used as the bone tissue engineering …

Different Inhibitory Effect and Mechanism of Hydroxyapatite Nanoparticles on Normal Cells and Cancer Cells In Vitro and In Vivo

Y Han, S Li, X Cao, L Yuan, Y Wang, Y Yin, T Qiu… - Scientific reports, 2014 - nature.com
Hydroxyapatite (HAP), similar to inorganic phase in bones, shows good biocompatibility and
bioactivity as bone defect repairing material. Recently, nanoscaled HAP shows the special …

Alginate-nanohydroxyapatite hydrogel system: Optimizing the formulation for enhanced bone regeneration

J Barros, MP Ferraz, J Azeredo, MH Fernandes… - Materials Science and …, 2019 - Elsevier
Ceramic/polymer-based biocomposites have emerged as potential biomaterials to fill,
replace, repair or regenerate injured or diseased bone, due to their outstanding features in …

Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes

US Gaharwar, R Meena… - Journal of Applied …, 2017 - Wiley Online Library
Over the past few decades nanotechnology and material science has progressed extremely
rapidly. Iron oxide nanoparticles (IONPs) owing to their unique magnetic properties have a …

Antitumor effect by hydroxyapatite nanospheres: Activation of mitochondria-dependent apoptosis and negative regulation of phosphatidylinositol-3-kinase/protein …

H Zhao, C Wu, D Gao, S Chen, Y Zhu, J Sun, H Luo… - ACS …, 2018 - ACS Publications
Hydroxyapatite nanoparticles (HA NPs) have been acknowledged for their benign
biocompatibility and proliferation inhibition effect on tumor cells, attracting considerable …