Semaphorins are key players in the control of neural circuit development. Recent studies
have uncovered several exciting and novel aspects of neuronal semaphorin signalling in …

Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …

Metzincin metalloproteases have major roles in intercellular communication by modulating
the function of membrane proteins. One of the proteases is the a-disintegrin-and …

NrCAM is a neuronal cell adhesion molecule of the L1 family of immunoglobulin super
family. It plays a wide variety of roles in neural development, including cell proliferation and …

Precise wiring of neural circuits is essential for brain connectivity and function. During
development, axons respond to diverse cues present in the extracellular matrix or at the …

Thalamocortical axons must cross a complex cellular terrain through the developing
forebrain, and this terrain has to be understood for us to learn how thalamocortical axons …

In this review we discuss recent advances in the understanding of the development of
forebrain projections attending to their origin, fate determination, and axon guidance. Major …

Neocortex functioning relies on the formation of complex networks that begin to be
assembled during embryogenesis by highly stereotyped processes of cell migration and …

MicroRNAs (miRNAs) have recently come to be viewed as critical players that modulate a
number of cellular features in various biological systems including the mature CNS by …

The Class 3 Semaphorins (Sema3s) are a sub-family of proteins whose known biological
roles are varied and growing. The mechanism of action of the Sema3s requires binding to …