Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target
tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however, leverages the immune …

Cancer is considered a life-threatening disease, and several factors are involved in its
development. Chemokines are small proteins that physiologically exert pivotal roles in …

To improve response rate of monotherapy of immune checkpoint blockade (ICB), it is
necessary to find an emerging target in combination therapy. Through analyzing tumor …

Background A growing number of studies found inconsistent results on the role of
chemokines in the progression of type 2 diabetes (T2DM) and prediabetes (PDM). The …

Esophageal cancer (EC) is frequently considered a lethal malignancy and is often identified
at a later stage. It is one of the major causes of cancer-related deaths globally. The …

Aim: To develop synergistic chemo-photothermal and ferroptosis therapy nanoparticles to
improve the efficacy of treatment for esophageal cancer. Materials & methods: Fe3O4@ PDA …

Cancer immunotherapy moderates the immune system's ability to fight cancer. Due to its
extreme complexity, scientists are working to put together all the puzzle pieces to get a …

Cancer-associated fibroblasts (CAFs) play vital roles in establishing a suitable tumor
microenvironment. In this study, RNA sequencing data revealed that CAFs could promote …

Tumorigenesis is a complicated process caused by successive genetic and epigenetic
alterations. The past decades demonstrated that the immune system affects tumorigenesis …

Cancer is a devastating disease and the primary cause of morbidity and mortality worldwide,
with cancer metastasis responsible for 90% of cancer-related deaths. Cancer metastasis is a …