Management of fatigue in rheumatoid arthritis

JE Pope - RMD open, 2020 - rmdopen.bmj.com
Fatigue in rheumatoid arthritis is highly prevalent. It is correlated only weakly with disease
activity but more so with pain, mood, personality features, poor sleep, obesity and …

Neuroendocrine and neurophysiological effects of interleukin 6 in rheumatoid arthritis

EHS Choy, LH Calabrese - Rheumatology, 2018 - academic.oup.com
RA is a chronic, systemic, autoimmune disease characterized by inflammation and
degradation of the joints, causing significant negative impact on quality of life. In addition to …

Olokizumab, a monoclonal antibody against interleukin 6, in combination with methotrexate in patients with rheumatoid arthritis inadequately controlled by …

E Nasonov, S Fatenejad, E Feist, M Ivanova… - Annals of the …, 2022 - ard.bmj.com
Objective To evaluate the efficacy and safety of olokizumab (OKZ) in patients with active
rheumatoid arthritis despite treatment with methotrexate (MTX). Methods In this 24-week …

To eat or not to eat—An exploratory randomized controlled trial on fasting and plant-based diet in rheumatoid arthritis (NutriFast-Study)

AM Hartmann, M Dell'Oro, M Spoo, JM Fischer… - Frontiers in …, 2022 - frontiersin.org
Background Fasting is beneficial in many diseases, including rheumatoid arthritis (RA), with
lasting effects for up to 1 year. However, existing data dates back several decades before …

Effectiveness of a treat-to-target strategy in patients with moderate to severely active rheumatoid arthritis treated with abatacept

L Bessette, B Haraoui, E Rampakakis… - Arthritis Research & …, 2023 - Springer
Background To compare a treat-to-target (T2T) approach and routine care (RC) in adults
with active to severely active rheumatoid arthritis (RA) initiating subcutaneous abatacept …

Nonpharmacological treatment in established rheumatoid arthritis

AA Küçükdeveci - Best Practice & Research Clinical Rheumatology, 2019 - Elsevier
The goals in the management of established rheumatoid arthritis (RA) are to control pain
and disease activity, prevent further joint damage, and enhance functioning and quality of …

Upadacitinib in rheumatoid arthritis: a benefit–risk assessment across a phase III program

PG Conaghan, E Mysler, Y Tanaka… - Drug Safety, 2021 - Springer
Treating to a target of clinical remission or low disease activity is an important principle for
managing rheumatoid arthritis (RA). Despite the availability of biologic disease-modifying …

Use of daily electronic patient-reported outcome (PRO) diaries in randomized controlled trials for rheumatoid arthritis: rationale and implementation

CO Bingham, CL Gaich, AM DeLozier, KD Engstrom… - Trials, 2019 - Springer
Background Rheumatoid arthritis (RA) is associated with significantly diminished health-
related quality of life. Patient-reported outcomes (PROs) are considered important in RA; …

Mapping between measurement scales in meta‐analysis, with application to measures of body mass index in children

AL Davies, AE Ades, JPT Higgins - Research Synthesis …, 2024 - Wiley Online Library
Quantitative evidence synthesis methods aim to combine data from multiple medical trials to
infer relative effects of different interventions. A challenge arises when trials report …

Effects on health-related quality of life in the randomized, controlled crossover trial ADIRA (Anti-inflammatory Diet In Rheumatoid Arthritis)

A Turesson Wadell, L Bärebring, E Hulander… - PloS one, 2021 - journals.plos.org
Background Patients with Rheumatoid Arthritis (RA) often report impaired health-related
quality of life (HrQoL) such as difficulties in daily life, pain, fatigue and an affected social life …