New perspectives of the role of skeletal muscle derived extracellular vesicles in the pathogenesis of amyotrophic lateral sclerosis: the 'dying back'hypothesis
C Sbarigia, S Rome, L Dini… - Journal of Extracellular …, 2024 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative disease that affects
nerve cells in the brain and the spinal cord, and is characterized by muscle weakness …
nerve cells in the brain and the spinal cord, and is characterized by muscle weakness …
The role of exosomal molecular cargo in exosome biogenesis and disease diagnosis
M Liu, Z Wen, T Zhang, L Zhang, X Liu… - Frontiers in …, 2024 - frontiersin.org
Exosomes represent a type of extracellular vesicles derived from the endosomal pathway
that transport diverse molecular cargoes such as proteins, lipids, and nucleic acids. These …
that transport diverse molecular cargoes such as proteins, lipids, and nucleic acids. These …
Nisin A elevates adenosine to achieve anti-inflammatory activity
Y Li, Y Wang, S Yan, Y Li, X Gao, J Yu, S Chen, P Li… - Food & Function, 2024 - pubs.rsc.org
Inflammation is a ubiquitous physiological status that exists during the occurrence,
development and prognosis of numerous diseases. Clinical anti-inflammatory drugs mainly …
development and prognosis of numerous diseases. Clinical anti-inflammatory drugs mainly …
[HTML][HTML] Immunomodulation with M2 macrophage–derived extracellular vesicles for enhanced titanium implant osseointegration under diabetic conditions
Y Cheng, X Dong, J Shi, G Wu, P Tao, N Ren, Y Zhao… - Materials Today Bio, 2025 - Elsevier
M2 macrophage–derived extracellular vesicles (M2-EVs) demonstrate the capacity to
reduce pro-inflammatory M1 macrophage formation, thereby restoring the M1–M2 …
reduce pro-inflammatory M1 macrophage formation, thereby restoring the M1–M2 …
Macrophage-derived extracellular vesicles from Ascaris lumbricoides antigen exposure enhance Mycobacterium tuberculosis growth control, reduce IL-1β, and …
G Pushpamithran, R Blomgran - Frontiers in Immunology, 2024 - frontiersin.org
Background Helminth coinfection with tuberculosis (TB) can alter the phenotype and
function of macrophages, which are the major host cells responsible for controlling …
function of macrophages, which are the major host cells responsible for controlling …
Tetrahedral Framework Nucleic Acid Relieves Sepsis‐Induced Intestinal Injury by Regulating M2 Macrophages
T Tan, J Li, W Fan, K Shang, C Yang, X Liu… - Cell …, 2025 - Wiley Online Library
This study aimed to clarify the role and mechanism of tetrahedral framework nucleic acids
(tFNAs) in regulating M2 macrophages to reduce intestinal injury. An intestinal injury model …
(tFNAs) in regulating M2 macrophages to reduce intestinal injury. An intestinal injury model …
[HTML][HTML] Ribes fasciculatum var. Chinense leaf extract alleviates muscle atrophy caused by chronic inflammatory conditions through suppressing polarization into M1 …
Y Seo, E Lee, JO Nam - Journal of Functional Foods, 2024 - Elsevier
Abstract Scope Ribes fasciculatum Siebold & Zucc. var. chinense Maxim. Leave extract
(RFE) has been reported to be non-toxic and suitable for consumption as a food, with …
(RFE) has been reported to be non-toxic and suitable for consumption as a food, with …
Exploring the mechanism and crosstalk between IL-6 and IL-1β on M2 macrophages under metabolic stress conditions
S Yadav, A Prasannan, K Venkatachalam, A Binesh - Cytokine, 2025 - Elsevier
Macrophages are highly variable immune cells that are important in controlling inflammation
and maintaining tissue balance. The ability to polarize into two major types—M1, promoting …
and maintaining tissue balance. The ability to polarize into two major types—M1, promoting …
Exosomes and Macrophages: Bidirectional Mutual Regulation in the Treatment of Diabetic Complications
X Li, L Yang, S Xu, Y Tian, X Meng - Cellular and Molecular …, 2024 - Springer
Purpose The bidirectional regulation of macrophages and exosomes provides a meaningful
research direction for the treatment of complications arising from both type 1 and type 2 …
research direction for the treatment of complications arising from both type 1 and type 2 …
Extrusomas de células natural killer: Vesículas artificiales derivadas de células como una alternativa innovadora de encapsulamiento de fármacos para el cáncer de …
JV Carrasco Rojas - 2024 - repositorio.udd.cl
El cáncer de pulmón (CP) tiene la tasa de mortalidad más alta a nivel mundial. Su
patogénesis es multifactorial y, aunque se recomiendan terapias dirigidas, muchos …
patogénesis es multifactorial y, aunque se recomiendan terapias dirigidas, muchos …