Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections
and malignancies. NK cells express a variety of inhibitory and activating receptors that …

Understanding how signals are integrated to control natural killer (NK) cell responsiveness
in the absence of antigen-specific receptors has been a challenge, but recent work has …

Natural killer (NK) cells can be swiftly mobilized by danger signals and are among the
earliest arrivals at target organs of disease. However, the role of NK cells in mounting …

For many years, vitamin D has been acknowledged for its role in maintaining calcium and
phosphate balance. However, in recent years, research has assessed its …

Human natural killer (NK) cells have distinct functions as NK tolerant, NK cytotoxic and NK
regulatory cells and can be divided into different subsets based on the relative expression of …

Vitamin D deficiency has been associated with a wide range of diseases and multiple forms
of cancer including breast, colon, and prostate cancers. Relatively recent work has …

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous
system (CNS) resulting from a breakdown in peripheral immune tolerance. Although a …

The PTPN22 locus is one of the strongest risk factors outside of the major histocompatability
complex that associates with autoimmune diseases. PTPN22 encodes lymphoid protein …

With an array of activating and inhibitory receptors, natural killer (NK) cells can specifically
eradicate infected and transformed cells. Target cell killing is achieved through directed …

Natural killer (NK) cells represent key innate immune cells that restrain viral infection and
malignant transformation and help mount an adaptive immune response. To perform such …