New insights on Drosophila antimicrobial peptide function in host defense and beyond

MA Hanson, B Lemaitre - Current Opinion in Immunology, 2020 - Elsevier
Highlights•Drosophila AMPs contribute to host defense, notably against Gram-negative
bacteria.•Certain AMPs show exquisite specifity against certain pathogens.•Certain AMPs …

Applications of next generation sequencing in molecular ecology of non-model organisms

R Ekblom, J Galindo - Heredity, 2011 - nature.com
As most biologists are probably aware, technological advances in molecular biology during
the last few years have opened up possibilities to rapidly generate large-scale sequencing …

Host biology in light of the microbiome: ten principles of holobionts and hologenomes

SR Bordenstein, KR Theis - PLoS biology, 2015 - journals.plos.org
Groundbreaking research on the universality and diversity of microorganisms is now
challenging the life sciences to upgrade fundamental theories that once seemed …

Phylosymbiosis: relationships and functional effects of microbial communities across host evolutionary history

AW Brooks, KD Kohl, RM Brucker, EJ van Opstal… - PLoS …, 2016 - journals.plos.org
Phylosymbiosis was recently proposed to describe the eco-evolutionary pattern, whereby
the ecological relatedness of host-associated microbial communities parallels the phylogeny …

The Hologenomic Basis of Speciation: Gut Bacteria Cause Hybrid Lethality in the Genus Nasonia

RM Brucker, SR Bordenstein - Science, 2013 - science.org
Although the gut microbiome influences numerous aspects of organismal fitness, its role in
animal evolution and the origin of new species is largely unknown. Here we present …

Speciation by symbiosis

RM Brucker, SR Bordenstein - Trends in ecology & evolution, 2012 - cell.com
In the Origin of Species, Darwin struggled with how continuous changes within a species
lead to the emergence of discrete species. Molecular analyses have since identified nuclear …

Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria

IS Pais, RS Valente, M Sporniak, L Teixeira - PLoS biology, 2018 - journals.plos.org
Animals live together with diverse bacteria that can impact their biology. In Drosophila
melanogaster, gut-associated bacterial communities are relatively simple in composition but …

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

K Schroder, KM Irvine, MS Taylor… - Proceedings of the …, 2012 - National Acad Sciences
Evolutionary change in gene expression is generally considered to be a major driver of
phenotypic differences between species. We investigated innate immune diversification by …

Insect immunity to entomopathogenic fungi

HL Lu, RJS Leger - Advances in genetics, 2016 - Elsevier
The study of infection and immunity in insects has achieved considerable prominence with
the appreciation that their host defense mechanisms share many fundamental …

Adaptive protein evolution in animals and the effective population size hypothesis

N Galtier - PLoS genetics, 2016 - journals.plos.org
The rate at which genomes adapt to environmental changes and the prevalence of adaptive
processes in molecular evolution are two controversial issues in current evolutionary …