Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

Covering: up to July 2023 Terpene cyclases (TCs) catalyze some of the most complicated
reactions in nature and are responsible for creating the skeletons of more than 95 000 …

As a midsized gene family conserved more by lineage than function, the typical plant
terpene synthases (TPSs) could be a valuable tool to examine plant evolution. TPSs are …

Covering: up to 2021 Terpenoids are a diverse group of chemicals used in a wide range of
industries. Microbial terpenoid production has the potential to displace traditional …

A grand challenge in terpene synthase (TS) enzymology is the ability to predict function from
protein sequence. Given the limited number of characterized bacterial TSs and significant …

Terpene synthases are capable of mediating complex reactions, but fundamentally simply
catalyze lysis of allylic diphosphate esters with subsequent deprotonation. Even with the …

The presence of anticancer clerodane diterpenoids is a chemotaxonomic marker for the
traditional Chinese medicinal plant Scutellaria barbata, although the molecular mechanisms …

The diverse class of plant diterpenoid metabolites serves important functions in mediating
growth, chemical defence, and ecological adaptation. In major monocot crops, such as …

An extract of the coralline demosponge Astrosclera willeyana inhibited the ubiquitin ligase
activity of the immunomodulatory protein Cbl-b. The bioassay-guided separation of the …

Abstract Investigation of the South China Sea nudibranch Hexabranchus sanguineus from
Sanya Bay afforded, in addition to three known compounds, nine new diterpenoids of the 5 …