Autonomic manifestations of epilepsy: emerging pathways to sudden death?

RD Thijs, P Ryvlin, R Surges - Nature Reviews Neurology, 2021 - nature.com
Epileptic networks are intimately connected with the autonomic nervous system, as
exemplified by a plethora of ictal (during a seizure) autonomic manifestations, including …

The burden of epilepsy and unmet need in people with focal seizures

P Ioannou, DL Foster, JW Sander, S Dupont… - Brain and …, 2022 - Wiley Online Library
Background Epilepsy is one of the most common neurological conditions worldwide. As a
chronic condition, epilepsy imposes a significant burden on people with epilepsy and …

The SANTÉ study at 10 years of follow‐up: effectiveness, safety, and sudden unexpected death in epilepsy

V Salanova, MR Sperling, RE Gross, CP Irwin… - …, 2021 - Wiley Online Library
Objective We evaluated the efficacy and safety of deep brain anterior thalamus stimulation
after 7 and 10 years, and report the incidence of sudden unexpected death in epilepsy …

[HTML][HTML] Histopathological findings in brain tissue obtained during epilepsy surgery

I Blumcke, R Spreafico, G Haaker… - … England Journal of …, 2017 - Mass Medical Soc
Background Detailed neuropathological information on the structural brain lesions
underlying seizures is valuable for understanding drug-resistant focal epilepsy. Methods We …

Timing of referral to evaluate for epilepsy surgery: Expert Consensus Recommendations from the Surgical Therapies Commission of the International League Against …

L Jehi, N Jette, CS Kwon, CB Josephson… - …, 2022 - Wiley Online Library
Epilepsy surgery is the treatment of choice for patients with drug‐resistant seizures. A timely
evaluation for surgical candidacy can be life‐saving for patients who are identified as …

Clinical risk factors in SUDEP: a nationwide population-based case-control study

O Sveinsson, T Andersson, P Mattsson, S Carlsson… - Neurology, 2020 - AAN Enterprises
Objective We conducted a nationwide case-control study in Sweden to test the hypothesis
that specific clinical characteristics are associated with increased risk of sudden unexpected …

Getting the best outcomes from epilepsy surgery

VN Vakharia, JS Duncan, JA Witt, CE Elger… - Annals of …, 2018 - Wiley Online Library
Neurosurgery is an underutilized treatment that can potentially cure drug‐refractory
epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to …

What can we do for people with drug-resistant epilepsy? The 2016 Wartenberg Lecture

J Engel Jr - Neurology, 2016 - AAN Enterprises
Treatment goals for epilepsy are no seizures, no side effects, as soon as possible, but these
goals are too often unmet. Approximately 1 million people in the United States continue to …

The current place of epilepsy surgery

J Engel Jr - Current opinion in neurology, 2018 - journals.lww.com
Surgical treatment for epilepsy remains underutilized, in part because of persistent
misconceptions. Rather than promote referral for surgery, it would be more appropriate to …

Epilepsy in Asia: disease burden, management barriers, and challenges

E Trinka, P Kwan, BI Lee, A Dash - Epilepsia, 2019 - Wiley Online Library
This article reviews the burden of epilepsy in Asia, the challenges faced by people with
epilepsy, and the management of epilepsy. Comparison is made with other parts of the …