Recent Applications and Trends in the Julia‐Kocienski Olefination

PXT Rinu, S Radhika, G Anilkumar - ChemistrySelect, 2022 - Wiley Online Library
Abstract The Julia‐Kocienski (J‐K) olefination is a modified version of Julia‐Lythgoe
olefination. In this reaction, an aldehyde or ketone is coupled with heterocycle‐bearing …

Stereoselective synthesis of 2, 6-disubstituted piperidine alkaloids

N Srivastava, L Macha, HJ Ha - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
Among the large number of structurally diverse alkaloids, 2, 6-disubstituted piperidine and
its analogs have often been targeted when exploiting new synthetic techniques perhaps …

[HTML][HTML] Visible-light-induced nickel-catalyzed cross-coupling with alkylzirconocenes from unactivated alkenes

Y Gao, C Yang, S Bai, X Liu, Q Wu, J Wang, C Jiang… - Chem, 2020 - cell.com
Transition-metal-catalyzed cross-coupling reactions between naturally abundant sp 3-
hybridized carbon centers facilitate access to diverse molecules with complex three …

Stereoselective strategies for the construction of polysubstituted piperidinic compounds and their applications in natural products' synthesis

N Kandepedu, I Abrunhosa-Thomas… - Organic Chemistry …, 2017 - pubs.rsc.org
Nitrogen-encompassing bioactive molecules can be regarded as the most frequently cited
moieties, occurring either as natural products or as synthetically constructed chemical …

Total synthesis and absolute stereochemical assignment of microgrewiapine A and its stereoisomers

L Macha, HJ Ha - The Journal of Organic Chemistry, 2018 - ACS Publications
Total synthesis of both enantiomers of (−)-(2 S, 3 R, 6 S)-and (+)-(2 R, 3 S, 6 R)-
microgrewiapine A along with (+)-microcosamine A and (−)-6-epi-microgrewiapine A from …

A review of chemistry and pharmacology of Piperidine alkaloids of Pinus and related genera

L Singh, AK Upadhyay, P Dixit, A Singh… - Current …, 2022 - ingentaconnect.com
Background: Pinus belongs to the family Pinaceae, represented by several species across
the globe. Various parts of the plant including needles are rich in biologically active …

[PDF][PDF] 深海来源微生物乙酰酯酶的酶学性质鉴定及拆分制备D-乳酸甲酯

黄锦龙, 张继福, 胡洁莹, 关见留, 张云, 孙爱君… - 热带海洋学报, 2018 - jto.ac.cn
D-乳酸及其酯是重要的手性药物中间体和手性化工产品. 从南海深海芽孢杆菌Bacillus sp.
SCSIO15029 克隆到一个乙酰酯酶基因bae02030, 表达并鉴定该酶Bae02030 的酶学性质 …

Aziridines and 2H-Azirines—Monocyclic

S Tarannum, N Chauhan… - Reference Module in …, 2020 - repository.ias.ac.in
The saturated small ring azaheterocycle aziridine and its unsaturated analogue azirine are
versatile intermediates and reaction partners for the synthesis of structurally and functionally …

Ex-Chiral-Pool Synthesis of Optically Active 4-Alkylidene-Tetrahydroisoquinolines–Key Intermediates for Crinane Alkaloid Total Syntheses

S Bernhard, N Kümmerer, D Urgast, F Hack… - …, 2024 - thieme-connect.com
A seven-step ex-chiral-pool synthesis of optically active 4-alkylidenetetrahydroisoquinolines
was developed. Starting from 6-bromopiperonal and (S)-serine esters, N-benzylation via …

Asymmetric synthesis of 2, 3, 6-trisubstituted piperidines via baylis–hillman adducts and lithium amide through domino reaction

MM Salgado, A Manchado, CT Nieto, D Díez… - Synlett, 2020 - thieme-connect.com
A convenient asymmetric synthesis of methyl (2S, 3S, 6R)-6-(4-fluorophenyl)-2-(4-
hydroxyphenyl)-piperidine-3-carboxylate is described, starting from Baylis–Hillman adducts …