Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Fluorinated molecules have a wide range of applications and are used as medicines,
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …

C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

This Review summarizes advances in fluorination by C (sp2)− H and C (sp3)− H activation.
Transition‐metal‐catalyzed approaches championed by palladium have allowed the …

The selective functionalization of remote C–H bonds via intramolecular hydrogen atom
transfer (HAT) is transformative for organic synthesis. This radical-mediated strategy …

We report the reprogramming of nonheme iron enzymes to catalyze an abiological C (sp3)‒
H azidation reaction through iron-catalyzed radical relay. This biocatalytic transformation …

A photoinduced cascade strategy leading to a variety of differentially functionalised nitriles
and ketones has been developed. These reactions rely on the oxidative generation of iminyl …

Cross-coupling reaction between two C–H bonds has become a fundamental strategy in
synthetic organic chemistry. With its increasing importance in green chemistry, atom …

Direct amination of C (sp3)− H bonds is of broad interest in the realm of C− H
functionalization because of the prevalence of nitrogen heterocycles and amines in …

The selective functionalization of C (sp3)− H bonds at distal positions to functional groups is
a challenging task in synthetic chemistry. Reported here is a photoinduced radical cascade …