The SOX proteins belong to the superfamily of transcription factors (TFs) that display
properties of both classical TFs and architectural components of chromatin. Since the …

Members of the SOX family of transcription factors are found throughout the animal kingdom,
are characterized by the presence of a DNA-binding HMG domain, and are involved in a …

Waardenburg syndrome (WS) is characterized by the association of pigmentation
abnormalities, including depigmented patches of the skin and hair, vivid blue eyes or …

▪ Abstract The first mouse microphthalmia transcription factor (Mitf) mutation was discovered
over 60 years ago, and since then over 24 spontaneous and induced mutations have been …

The molecular mechanisms that determine glial cell fate in the vertebrate nervous system
have not been elucidated. Peripheral glial cells differentiate from pluripotent neural crest …

Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found
throughout the animal kingdom. They are involved in the regulation of such diverse …

Sox10 transcription factor is expressed in schwannian and melanocytic lineages and is
important in their development and can be used as a marker for corresponding tumors. In …

Enteric glial cells are vital for the autonomic control of gastrointestinal homeostasis by the
enteric nervous system. Several different functions have been assigned to enteric glial cells …

The SOX family of high-mobility group (HMG) domain proteins has recently been recognized
as a key player in the regulation of embryonic development and in the determination of the …

Maintain stemness, commit to a specific lineage, differentiate, proliferate, or die. These are
essential decisions that every cell is constantly challenged to make in multi-cellular …