Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer's disease

NM Abdelmaksoud, AAM Sallam, AI Abulsoud… - … -Research and Practice, 2024 - Elsevier
Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

AS Doghish, O Elazazy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: a review focus on signaling pathways

AS Doghish, MB Zaki, MG Eldeib, AF Radwan… - … -Research and Practice, 2024 - Elsevier
Colorectal cancer (CRC) is one of the most frequent cancers in incidence and mortality.
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …

Deciphering signaling pathway interplay via miRNAs in malignant pleural mesothelioma

A Salman, SSA Mageed, D Fathi, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly invasive form of lung cancer that
adversely affects the pleural and other linings of the lungs. MPM is a very aggressive tumor …

Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways

AS Doghish, AA El-Husseiny, EG Khidr… - … -Research and Practice, 2023 - Elsevier
Oral cancer (OC) is the predominant type originating in the head and neck region. The
incidence of OC is mostly associated with behavioral risk factors, including tobacco smoking …

Harnessing the power of miRNAs: the molecular architects of asthma pathogenesis and potential targets for therapeutic innovation

TM Al-Noshokaty, D Fathi, AI Abulsoud… - … -Research and Practice, 2024 - Elsevier
Asthma is a chronic non-communicable respiratory disease that is characterized by airway
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …

Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of oral cancer

AS Doghish, SS Elshaer, D Fathi, NI Rizk… - … -Research and Practice, 2024 - Elsevier
Oral cancer (OC) is a widely observed neoplasm on a global scale. Over time, there has
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …

Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Parkinson's disease

OA Mohammed, MS Elballal, AA El-Husseiny… - … -Research and Practice, 2024 - Elsevier
Parkinson's disease (PD) is a debilitating neurological disorder characterized by the
impairment of the motor system, resulting in symptoms such as resting tremor, cogwheel …

The emerging role of miRNAs in myocardial infarction: From molecular signatures to therapeutic targets

OA Mohammed, M Alghamdi, J Alfaifi… - … -Research and Practice, 2024 - Elsevier
Globally, myocardial infarction (MI) and other cardiovascular illnesses have long been
considered the top killers. Heart failure and mortality are the results of myocardial apoptosis …

Modulation of ferroptosis by non‑coding RNAs in cancers: Potential biomarkers for cancer diagnose and therapy

H Gong, Z Li, Z Wu, G Lian, Z Su - Pathology-Research and Practice, 2024 - Elsevier
Ferroptosis is a recently discovered cell programmed death. Extensive researches have
indicated that ferroptosis plays an essential role in tumorigenesis, development, migration …