Conspectus For a long time, peptides were considered unsuitable for drug development due
to their inherently poor pharmacokinetic properties and proteolytic susceptibility. However …

Peptides have been heavily investigated for their biocompatible and bioactive properties.
Though a wide array of functionalities can be introduced by varying the amino acid …

Conformationally ordered synthetic oligomers, also called “foldamers”, have attracted
considerable attention in recent years owing to their ability to mimic the structural …

Most of the structural studies made on the secondary structure of peptoids describe their
geometric attributes in terms of the classic Ramachandran plot (based on the local analysis …

Head-to-tail cyclization of N-substituted glycine peptoid oligomers is known to enforce their
conformational ordering. We now describe the installation of an additional covalent …

An aromatic peptoid analogue of the diphenylalanine dipeptide self-assembles in aqueous
solution and the first crystal structure was obtained for this class of compound. This reveals …

Macrocyclic arylopeptoids – a novel type of cyclic N -alkylated aromatic oligoamides forming
nanotubular assemblies - Chemical Communications (RSC Publishing) DOI:10.1039/C4CC00821A …

We describe the qualitative and quantitative analysis of the complexation properties towards
cations of a cyclic peptoid hexamer composed of alternating α-and β-peptoid monomers …

The presence of at least one N-Cα branched side chain is crucial for successful cyclization
of α, β-tetrapeptoids. The ctct amide sequence revealed in the crystal structure of the 14 …

The synthesis of β-peptoids (ie, N-substituted β-alanine oligomers) 10 or more residues in
length has proven challenging owing to poor coupling efficiency even after extended …