Background For several decades, intermediate metabolism and signal transduction have
been considered two independent entities. On one side stood the catabolic and anabolic …

Insect meals are novel and potentially sustainable protein sources. The objectives of this
study were to determine the chemical composition and standardized amino acid digestibility …

Summary Charcot-Marie-Tooth (CMT) disease is a clinically and genetically heterogeneous
distal symmetric polyneuropathy. Whole-exome sequencing (WES) of 40 individuals from 37 …

Mutations in GDAP1 lead to severe forms of the peripheral motor and sensory neuropathy,
Charcot-Marie-Tooth disease (CMT), which is characterized by heterogeneous phenotypes …

Mitochondria are at the center of cellular energy metabolism and regulate cell life and death.
The cell biological aspect of mitochondria, especially mitochondrial dynamics, has drawn …

Abstract Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous group of
disorders sharing the same clinical phenotype, characterized by distal limb muscle wasting …

Background: Charcot-Marie-Tooth disease (CMT) is the most common inherited
neuromuscular disorder and is characterized by significant clinical and genetic …

Peripheral nerves have peculiar energetic requirements because of considerable length of
axons and therefore correct mitochondria functioning and distribution along nerves is …

Abstract Introduction Mutations in GDAP1 (Ganglioside-induced differentiation-associated
protein 1) gene are linked to Charcot-Marie-Tooth disease (CMT), a Heterogenous group of …

Mutations in GDAP1, the ganglioside-induced differentiation-associated protein 1 gene,
cause Charcot–Marie–Tooth (CMT) type 4A, a severe autosomal recessive form of …