Adverse immune responses to foods affect approximately 5% of young children and 3% to
4% of adults in westernized countries and appear to have increased in prevalence. Food …

The TIM (T cell/transmembrane, immunoglobulin, and mucin) gene family plays a critical role
in regulating immune responses, including allergy, asthma, transplant tolerance …

Abstract Background Regulatory B (Breg) cells represent one of the B cell subsets that
infiltrate solid tumors and exhibit distinct phenotypes in different tumor microenvironments …

Food allergy affects more than 500 million people in the world, and its prevalence is
increasing at an alarming rate causing serious public health concerns; however, prevention …

Increasing age alters innate immune–mediated responses; however, the mechanisms
underpinning these changes in humans are not fully understood. Using a human dermal …

Biological therapies can be beneficial in cancer patients. The present study aims to examine
the inhibitory mechanism of curcumin on cancer cells in patients with colorectal cancer. The …

Dendritic cells (DCs) that express T cell immunoglobulin domain molecule-4 (TIM4), a cell
surface receptor for phosphatidylserine, induce T helper 2 (TH2) cell responses and allergic …

Dendritic cells (DCs) must achieve a critical balance between activation and tolerance, a
process influenced by cytokines and growth factors. IL-10, which transduces signals through …

Food allergies, defined as an adverse immune response to food proteins, affect as many as
6% of young children and 3%–4% of adults in westernized countries, and their prevalence …

Food allergy now affects 6%–8% of children in the Western world; despite this, we
understand little about why certain people become sensitized to food allergens. The …