New whole-genome alignment tools are needed for tapping into plant diversity

B Song, ES Buckler, MC Stitzer - Trends in Plant Science, 2024 - cell.com
Genome alignment is one of the most foundational methods for genome sequence studies.
With rapid advances in sequencing and assembly technologies, these newly assembled …

Pangenome graph construction from genome alignments with Minigraph-Cactus

G Hickey, J Monlong, J Ebler, AM Novak… - Nature …, 2024 - nature.com
Pangenome references address biases of reference genomes by storing a representative
set of diverse haplotypes and their alignment, usually as a graph. Alternate alleles …

The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding

X Shi, S Cao, X Wang, S Huang, Y Wang… - Horticulture …, 2023 - academic.oup.com
Grapevine is one of the most economically important crops worldwide. However, the
previous versions of the grapevine reference genome tipically consist of thousands of …

Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References

DJ Taylor, JM Eizenga, Q Li, A Das… - Annual Review of …, 2024 - annualreviews.org
The Human Genome Project was an enormous accomplishment, providing a foundation for
countless explorations into the genetics and genomics of the human species. Yet for many …

The gap-free genome of mulberry elucidates the architecture and evolution of polycentric chromosomes

B Ma, H Wang, J Liu, L Chen, X Xia, W Wei… - Horticulture …, 2023 - academic.oup.com
Mulberry is a fundamental component of the global sericulture industry, and its positive
impact on our health and the environment cannot be overstated. However, the mulberry …

Going broad and deep: sequencing‐driven insights into plant physiology, evolution, and crop domestication

S Gui, FJ Martinez‐Rivas, W Wen, M Meng… - The Plant …, 2023 - Wiley Online Library
Deep sequencing is a term that has become embedded in the plant genomic literature in
recent years and with good reason. A torrent of (largely) high‐quality genomic and …

Human pangenomics: promises and challenges of a distributed genomic reference

P Abondio, E Cilli, D Luiselli - Life, 2023 - mdpi.com
A pangenome is a collection of the common and unique genomes that are present in a given
species. It combines the genetic information of all the genomes sampled, resulting in a large …

Near chromosome–level genome assembly of the microsporidium Hamiltosporidium tvaerminnensis

P Angst, JF Pombert, D Ebert… - G3: Genes, Genomes …, 2023 - academic.oup.com
Microsporidia are intracellular parasitic fungi whose genomes rank among the smallest of all
known eukaryotes. A number of outstanding questions remain concerning the evolution of …

Parsnp 2.0: scalable core-genome alignment for massive microbial datasets

B Kille, MG Nute, V Huang, E Kim, AM Phillippy… - …, 2024 - academic.oup.com
Motivation Since 2016, the number of microbial species with available reference genomes in
NCBI has more than tripled. Multiple genome alignment, the process of identifying …

CoreDetector: a flexible and efficient program for core-genome alignment of evolutionary diverse genomes

M Fruzangohar, P Moolhuijzen, N Bakaj… - Bioinformatics, 2023 - academic.oup.com
Motivation Whole genome alignment of eukaryote species remains an important method for
the determination of sequence and structural variations and can also be used to ascertain …