The multifaceted profile of activated microglia

MA Lynch - Molecular neurobiology, 2009 - Springer
Although relatively neglected previously, research efforts in the past decade or so have
identified a pivotal role for glial cells in regulating neuronal function. Particular emphasis has …

Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms

F Alyu, M Dikmen - Acta neuropsychiatrica, 2017 - cambridge.org
ObjectiveEpilepsy is a chronic neurological disease characterised with seizures. The
aetiology of the most generalised epilepsies cannot be explicitly determined and the …

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

M Zeraati, N Najdi, B Mosaferi, AA Salari - Behavioural brain research, 2021 - Elsevier
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

[HTML][HTML] NLRP3 and NLRP1 inflammasomes are up-regulated in patients with mesial temporal lobe epilepsy and may contribute to overexpression of caspase-1 and …

EC de Brito Toscano, ÉLM Vieira, BBR Dias, MV Caliari… - Brain Research, 2021 - Elsevier
Inflammation plays a role in the pathophysiology of mesial temporal lobe epilepsy (MTLE).
Inflammasome pathways, including the NLRP1 and NLRP3-induced ones, promote …

Circulating cytokines as biomarkers of alcohol abuse and alcoholism

RN Achur, WM Freeman, KE Vrana - Journal of Neuroimmune …, 2010 - Springer
There are currently no consistent objective biochemical markers of alcohol abuse and
alcoholism. Development of reliable diagnostic biomarkers that permit accurate assessment …

Epilepsy: indian perspective

NS Santhosh, S Sinha… - Annals of Indian Academy …, 2014 - journals.lww.com
There are 50 million people living with epilepsy worldwide, and most of them reside in
developing countries. About 10 million persons with epilepsy are there in India. Many …

[HTML][HTML] IL-1β, IL-6 and IL1Ra levels in temporal lobe epilepsy

IF Uludag, T Duksal, BI Tiftikcioglu, Y Zorlu, F Ozkaya… - Seizure, 2015 - Elsevier
Purpose There is now extensive evidence to support the involvement of inflammation in the
course of epileptic seizures. Seizure-induced changes in serum IL-1β, IL-6 and IL-1Ra …

Expressions of tumor necrosis factor alpha and microRNA-155 in immature rat model of status epilepticus and children with mesial temporal lobe epilepsy

MU Ashhab, A Omran, H Kong, N Gan, F He… - Journal of Molecular …, 2013 - Springer
Recently, the role of inflammation has attracted great attention in the pathogenesis of mesial
temporal lobe epilepsy (MTLE), and microRNAs start to emerge as promising new players in …

Blood biomarkers in epilepsy

RK Banote, S Akel, J Zelano - Acta Neurologica Scandinavica, 2022 - Wiley Online Library
Robust and accessible biomarkers are greatly needed in epilepsy. Diagnostic and
prognostic precision in the clinic needs to improve, and there is a need for objective …

Behavioral comorbidities of epilepsy and neuroinflammation: Evidence from experimental and clinical studies

EM Suleymanova - Epilepsy & Behavior, 2021 - Elsevier
Currently, a significant amount of data is accumulated showing that neuroinflammation is
one of the key processes in the development of brain pathology in trauma …