Association of glycemic indices (hyperglycemia, glucose variability, and hypoglycemia) with oxidative stress and diabetic complications

E Papachristoforou, V Lambadiari… - Journal of diabetes …, 2020 - Wiley Online Library
Oxidative stress (OS) is defined as a disturbance in the prooxidant‐antioxidant balance of
the cell, in favor of the former, which results in the antioxidant capacity of the cell to be …

Cardiovascular biology of the incretin system

JR Ussher, DJ Drucker - Endocrine reviews, 2012 - academic.oup.com
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that enhances glucose-stimulated
insulin secretion and exerts direct and indirect actions on the cardiovascular system. GLP-1 …

[HTML][HTML] The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats

S Steven, M Oelze, A Hanf, S Kröller-Schön, F Kashani… - Redox biology, 2017 - Elsevier
Hyperglycemia associated with inflammation and oxidative stress is a major cause of
vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a …

Effect of multispecies probiotic supplements on metabolic profiles, hs-CRP, and oxidative stress in patients with type 2 diabetes

Z Asemi, Z Zare, H Shakeri, S Sabihi… - Annals of nutrition and …, 2013 - karger.com
Background: We are aware of no study that has indicated the effects of daily consumption of
multispecies probiotic supplements on metabolic profiles, high-sensitivity C-reactive protein …

Rodent models for metabolic syndrome research

SK Panchal, L Brown - BioMed Research International, 2011 - Wiley Online Library
Rodents are widely used to mimic human diseases to improve understanding of the causes
and progression of disease symptoms and to test potential therapeutic interventions …

Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials

Y Ruan, J Sun, J He, F Chen, R Chen, H Chen - PloS one, 2015 - journals.plos.org
Background Previous clinical trials indicate that probiotic consumption may improve blood
glucose control, however, results from randomized trials on glycemic control have been …

Effects of synbiotic food consumption on metabolic status of diabetic patients: a double-blind randomized cross-over controlled clinical trial

Z Asemi, A Khorrami-Rad, SA Alizadeh, H Shakeri… - Clinical nutrition, 2014 - Elsevier
Background & aims We are aware of no study indicating the effects of synbiotic food
consumption on metabolic profiles, inflammation and oxidative stress among diabetic …

Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes

JS Teodoro, S Nunes, AP Rolo, F Reis… - Frontiers in …, 2019 - frontiersin.org
Type 2 diabetes mellitus is a leading cause of morbidity and mortality worldwide, given its
serious associated complications. Despite constant efforts and intensive research, an …

The effects of dipeptidyl peptidase-4 inhibition on microvascular diabetes complications

A Avogaro, GP Fadini - Diabetes care, 2014 - Am Diabetes Assoc
We performed a review of the literature to determine whether the dipeptidyl peptidase-4
inhibitors (DPP4-I) may have the capability to directly and positively influence diabetic …

Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

S Kröller-Schön, M Knorr, M Hausding… - Cardiovascular …, 2012 - academic.oup.com
Abstract Aims Dipeptidyl peptidase-4 (DPP-4) inhibitors are a novel class of drugs for the
treatment of hyperglycaemia. Preliminary evidence suggests that their antioxidant and anti …