The cardio-oncologic burden of breast cancer: molecular mechanisms and importance of preclinical models

J Brauer, M Tumani, N Frey, LH Lehmann - Basic Research in Cardiology, 2024 - Springer
Breast cancer, the most prevalent cancer affecting women worldwide, poses a significant
cardio-oncological burden. Despite advancements in novel therapeutic strategies …

Cardiac toxicity from adjuvant targeting treatment for breast cancer post-surgery

Z Fu, Z Lin, M Yang, C Li - Frontiers in Oncology, 2022 - frontiersin.org
Breast cancer is one of the most prevalent types of cancers worldwide, especially for
females. Surgery is the preferred treatment for breast cancer, and various postoperative …

Cardiovascular disease incidence rates: a study using routinely collected health data

J Ramroth, R Shakir, SC Darby, DJ Cutter, V Kuan - Cardio-Oncology, 2023 - Springer
Background There is substantial evidence that systemic anticancer therapies and
radiotherapy can increase the long-term risk of cardiovascular disease (CVD). Optimal …

Anthracycline‑induced delayed‑onset cardiac toxicity: A case report and literature review

M Kong, Q Pan, X Cheng, J Li… - Experimental and …, 2023 - spandidos-publications.com
Anthracyclic (ANT) drugs are widely used for patients with malignant tumors and can
markedly prolong the disease‑free survival rate of patients. As its clinical application …

Cardiotoxicity and pharmacogenetics of doxorubicin in black Zimbabwean breast cancer patients

VA Nyangwara, T Mazhindu… - British Journal of …, 2024 - Wiley Online Library
Aims Doxorubicin‐induced cardiotoxicity (DIC) is a significant cause of mortality in cancer
care. This study was conducted to establish the frequency of DIC in Zimbabwean breast …

Protective effects of Panax ginseng against doxorubicin-induced cardiac toxicity in patients with non-metastatic breast cancer: A randomized, double-blind, placebo …

M Hamidian, F Foroughinia… - Journal of Oncology …, 2023 - journals.sagepub.com
Introduction Anthracycline-based chemotherapy increases the risk of cancer therapeutics-
related cardiac dysfunction. Recently, evidences from in vitro experiments and animal …

Profile, treatment patterns, and influencing factors of anthracycline use in breast cancer patients in China: A nation‐wide multicenter study

F Guo, Z Yi, W Wang, Y Han, P Yu, S Zhang… - Cancer …, 2021 - Wiley Online Library
Background Anthracycline‐based chemotherapy (ABC) is one of the standard therapies
against breast cancer. However, few guidelines are currently available to optimize the use of …

[HTML][HTML] New insights into cardioprotection in breast cancer patients undergoing physical exercise during chemotherapy: A systematic review and meta-analysis

BG Linhares, DG Linhares, G Boppre… - Current Problems in …, 2024 - Elsevier
Background: Chemotherapy associated with breast cancer often induces cardiotoxicity,
which compromises patients' health and quality of life. Objective: To verify the effect of …

Dose-dense sequential adjuvant chemotherapy in the trastuzumab era: final long-term results of the Hellenic Cooperative Oncology Group Phase III HE10/05 Trial

F Zagouri, GA Koliou, F Dimitrakopoulos… - British Journal of …, 2022 - nature.com
Background Dose-dense sequential chemotherapy with anthracyclines and taxanes
achieved an 18% reduction of recurrence risk in early breast cancer (BC). The optimal …

Cardiac toxicity of patients on short course trastuzumab in combination with chemotherapy (FinHer Protocol) in breast cancer

A TM, R Joseph P, AA Abraham, M Mathew… - The Breast …, 2021 - Wiley Online Library
FinHer regimen is considered a relatively cardiac safe regimen for Her 2 positive breast
cancer in resource‐limited settings. There is limited data on cardiotoxicity of this regimen …