Voltage-gated calcium channels are important regulators of brain, heart and muscle
functions, and their dysfunction can give rise to pathophysiological conditions ranging from …

Mechanosensation is the ability to detect dynamic mechanical stimuli (eg, pressure, stretch,
and shear stress) and is essential for a wide variety of processes, including our sense of …

Bioactive peptides (BAPs), derived through enzymatic hydrolysis of food proteins, have
demonstrated potential for application as health‐promoting agents against numerous …

In the early 1950s, Austin and Chang independently described the changes that are
required for the sperm to fertilize oocytes in vivo. These changes were originally grouped …

To facilitate studies of the yeast proteome, we cloned 5800 open reading frames and
overexpressed and purified their corresponding proteins. The proteins were printed onto …

The CDPK-SnRK superfamily consists of seven types of serine-threonine protein kinases:
calcium-dependent protein kinase (CDPKs), CDPK-related kinases (CRKs), phospho enol …

Highly pathogenic severe acute respiratory syndrome coronavirus (SARS-CoV) has
developed strategies to inhibit host immune recognition. We identify cellular E3 ubiquitin …

Many extracellular signals, including light, biotic, and abiotic stress factors, elicit changes in
cellular Ca2+ concentration in plants (Trewavas and Knight, 1994; Bush, 1995; Braam et al …

Calmodulin (CaM) is a ubiquitous, highly conserved, eukaryotic protein that binds to and
regulates a number of diverse target proteins involved in different functions such as …

Ischemic tissues require mechanisms to alert the immune system of impending cell damage.
The nuclear protein high-mobility group box 1 (HMGB1) can activate inflammatory pathways …