This study provides an in‐depth analysis of the distinct consequences of the opioid drugs
morphine and fentanyl during opioid‐induced respiratory depression (OIRD). We explored …

Respiration is governed by a central rhythm and pattern generator, which has the pre-
Bötzinger complex as the inspiratory oscillator initiating the coordinated activity of several …

Breathing behaviour involves the generation of normal breaths (eupnoea) on a timescale of
seconds and sigh breaths on the order of minutes. Both rhythms emerge in tandem from a …

The opioid health crisis is a complex and multifaceted public health emergency that has 34
been unfolding across the globe, with particularly devastating impacts in the United States. It …

How breathing is generated by the preBötzinger Complex (preBötC) remains divided
between two ideological frameworks, and the persistent sodium current (I NaP) lies at the …

The primary cause of death from opioid overdose is opioid-induced respiratory depression
(OIRD), characterized by severe suppression of respiratory rate, destabilized breathing …

Inhibitory neurons embedded within mammalian neural circuits shape breathing, walking,
chewing, and other rhythmic motor behaviors. At the core of the neural circuit controlling …

Inhibitory neurons embedded within mammalian neural circuits shape breathing, walking,
and other rhythmic motor behaviors. At the core of the neural circuit controlling breathing is …