Vitiligo: a focus on pathogenesis and its therapeutic implications

C Bergqvist, K Ezzedine - The Journal of dermatology, 2021 - Wiley Online Library
Vitiligo is the most common depigmenting disorder affecting 0.1%–2% of the population
worldwide. The characteristic white patches result from the selective loss of melanocytes …

Janus kinase inhibitors in the treatment of vitiligo: a review

F Qi, F Liu, L Gao - Frontiers in immunology, 2021 - frontiersin.org
Vitiligo is a multifactorial reversible skin disorder characterized by distinct white patches that
result from melanocyte destruction. Activated CXCR3+ CD8+ T cells promote melanocyte …

Anatomically distinct fibroblast subsets determine skin autoimmune patterns

Z Xu, D Chen, Y Hu, K Jiang, H Huang, Y Du, W Wu… - Nature, 2022 - nature.com
The skin serves as a physical barrier and an immunological interface that protects the body
from the external environment,–. Aberrant activation of immune cells can induce common …

Vitiligo: mechanisms of pathogenesis and treatment

ML Frisoli, K Essien, JE Harris - Annual review of immunology, 2020 - annualreviews.org
Vitiligo is an autoimmune disease of the skin that targets pigment-producing melanocytes
and results in patches of depigmentation that are visible as white spots. Recent research …

Update on the pathogenesis of vitiligo

HZ Marchioro, CCS Castro, VM Fava… - Anais Brasileiros de …, 2022 - SciELO Brasil
Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …

Vitiligo: focus on clinical aspects, immunopathogenesis, and therapy

K Boniface, J Seneschal, M Picardo, A Taïeb - Clinical reviews in allergy & …, 2018 - Springer
Vitiligo is an acquired chronic depigmenting disorder of the skin, with an estimated
prevalence of 0.5% of the general population, characterized by the development of white …

Vitiligo: a comprehensive overview: part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work …

A Alikhan, LM Felsten, M Daly… - Journal of the American …, 2011 - Elsevier
Vitiligo is an acquired pigmentary disorder of unknown etiology that is clinically
characterized by the development of white macules related to the selective loss of …

[HTML][HTML] Vitiligo skin is imprinted with resident memory CD8 T cells expressing CXCR3

K Boniface, C Jacquemin, AS Darrigade… - Journal of Investigative …, 2018 - Elsevier
Vitiligo is a chronic autoimmune depigmenting skin disorder that results from a loss of
melanocytes. Multiple combinatorial factors have been involved in disease development …

New discoveries in the pathogenesis and classification of vitiligo

M Rodrigues, K Ezzedine, I Hamzavi… - Journal of the American …, 2017 - Elsevier
Vitiligo is a common autoimmune disease that progressively destroys melanocytes in the
skin, resulting in the appearance of patchy depigmentation. This disfiguring condition …

Evidence for an autoimmune pathogenesis of vitiligo

K Ongenae, N Van Geel, JM Naeyaert - Pigment Cell Research, 2003 - Wiley Online Library
Vitiligo is a depigmenting disorder characterized by the development of white patches in
various distributions, which are due to the loss of melanocytes from the epidermis. A variety …