HPVs (human papillomaviruses) infect epithelial cells and cause a variety of lesions ranging
from common warts/verrucas to cervical neoplasia and cancer. Over 100 different HPV types …

Human papillomaviruses (HPVs) are a diverse group of viruses that cause epithelial lesions
of varying severity. Of the 100 or so types that have been identified, around 40 can infect the …

The E2 proteins from oncogenic (high-risk) human papillomaviruses (HPVs) can induce
apoptotic cell death in both HPV-transformed and non-HPV-transformed cells. Here we …

Cervical cancer incidence is tightly linked to HPV infection, and particularly virus types 16
and 18 cause the majority of cases presenting with pre-cancerous stages of cervical …

The human papillomavirus (HPV) E2 protein is essential for regulating the initiation of viral
DNA replication as well as the regulation of transcription of certain HPV-encoded genes. Its …

Human papillomavirus (HPV) gene expression is regulated in concert with the epithelial
differentiation program. In particular, expression of the virus capsid proteins L1 and L2 is …

DDX11/ChlR1 is a super-family two iron–sulfur cluster containing DNA helicase with roles in
DNA replication and sister chromatid cohesion establishment, and general chromosome …

E2 protein binding to the four E2 binding sites (E2BSs) at the long control region of Human
Papillomavirus (HPV) 16/18 genome may exert either transcriptional activation/repression …

Field cancerisation was originally described as a basis for multiple head and neck
squamous cell carcinoma (HNSCC) and is a pre-malignant phenomenon that is frequently …

Papillomavirus E2 protein is required for the replication and maintenance of viral genomes
and transcriptional regulation of viral genes. E2 functions through sequence-specific binding …