Abstract G‐quadruplexes (G4), found in numerous places within the human genome, are
involved in essential processes of cell regulation. Chromosomal DNA G4s are involved for …

Telomeres and their single stranded overhangs gradually shorten with successive cell
divisions, as part of the natural aging process, but can be elongated by telomerase, a …

Intramolecular guanine quadruplexes (G4s) are non-canonical nucleic acid structures
formed by four guanine (G)-rich tracts that assemble into a core of stacked planar tetrads. G4 …

Conserved telomere maintenance component 1 (CTC1) is an important component of the
CST (CTC1-STN1-TEN1) complex, involved in maintaining the stability of telomeric DNA …

Shelterin serves critical roles in suppressing superfluous DNA damage repair pathways on
telomeres. The junction between double-stranded telomeric tracts (dsTEL) and single …

We reported over 20 years ago MNS-4.1, the first DNA aptamer with a micromolar affinity for
cocaine. MNS-4.1 is based on a structural motif that is very common in any random pool of …

G-quadruplexes (G4s) are four-stranded structures formed by guanine-rich sequences.
While their structures, properties, and applications have been extensively studied, an …

Guanine quadruplexes (GQs) play crucial roles in various biological processes, and
understanding their folding pathways provides insight into their stability, dynamics, and …

Telomeres terminate with a 50–300 bases long single-stranded G-rich overhang, which can
be misrecognized as a DNA damage repair site. Shelterin plays critical roles in maintaining …

G-quadruplexes (G4s) are nucleic acid secondary structures detected within human
chromosomes, that cluster at gene promoters and enhancers. This suggests that G4s may …