This article comprises detailed information about L-asparaginase, encompassing topics
such as microbial and plant sources of L-asparaginase, treatment with L-asparaginase …

Objective. Vaccinations are the most important tool to prevent infectious diseases.
Chemotherapy‐induced immune depression may impact the efficacy of vaccinations in …

This report is a revision of General Recommendations on Immunization and updates the
2002 statement by the Advisory Committee on Immunization Practices (ACIP)(CDC. General …

This report is a revision of the General Recommendations on Immunization and updates the
2006 statement by the Advisory Committee on Immunization Practices (ACIP)(CDC. General …

Intensified chemotherapy regimens resulting in improved survival of children with acute
lymphocytic leukemia (ALL) lead to concerns about therapy-induced immune damage …

Acute lymphoblastic leukaemia (ALL) is one of the leading types of malignant disorder seen
in children. Viral infections, genetic factors and exposure to chemical carcinogens are some …

Background Intensive chemotherapy in children with cancer results in long-term impairment
of humoral immunity. Whereas most studies to date focused on children with acute …

Introduction of Haemophilus influenzae type b (Hib) conjugate vaccines in late 1980s–early
1990s made a dramatic effect on the incidence of invasive Hib disease among children in …

Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for
hematological malignancies are at high risk of infections. 1 The synergy of transplant …

Children with cancer may be immunocompromised as a result of their primary underlying
disease and/or the use of prolonged and intensive chemotherapy administered with or …