Introduction Fibroblast activation protein-α (FAPα) is overexpressed on cancer-associated
fibroblasts in approximately 90% of epithelial neoplasms, representing an appealing target …

Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …

Fibroblast activation protein inhibitor (FAPI) PET/CT is a new tool in the diagnostic workup of
cancer. With a growing volume of applications, pitfalls and common findings need to be …

Fibroblast activation protein inhibitor (FAPI) is a promising tracer in oncologic positron
emission tomography/computed tomography (PET/CT). Numerous studies have …

Fibroblast-activation protein (FAP) is a serine protease classified in the dipeptidyl peptidase
4 (DPP4) family. FAP is predominantly expressed in activated fibroblasts such as the cancer …

Introduction: There is a pressing demand for the development of cancer-specific diagnostic
imaging tools, particularly for staging of pancreatic-, gastric-or cholangiocarcinoma, as …

Background. Cancer‐associated fibroblasts (CAFs) can strongly modulate the response to
therapy of malignant tumor cells, facilitating their continuous proliferation and invading …

Radiolabeled FAPI (fibroblast activation protein inhibitors) recently gained attention as
widely applicable imaging and potential therapeutic compounds targeting CAF (cancer …

Objective To systematically investigate the physiological distribution and benign lesion
incidental uptake of Al 18 F-NOTA-FAPI-04 (18 F-FAPI) in cancer patients to establish the …

Cancer is the leading cause of death around the globe, followed by heart disease and
stroke, with the highest mortality to this day. We have reached great levels of understanding …