Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

PURPOSE OF REVIEW Traumatic brain injury (TBI) encompasses a group of
heterogeneous manifestations of a disease process with high neurologic morbidity and, for …

The development of implantable neuroelectrodes is advancing rapidly as these tools are
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …

Neuroinflammation is critical in the pathogenesis of neurological diseases. Microglial pro-
inflammatory (M1) and anti-inflammatory (M2) status determines the outcome of …

Background. Exposure of infant animals to clinically used anaesthetics is associated with
acute structural brain abnormalities and development functional alterations. The α2 …

Background The α 2-adrenoreceptor agonist dexmedetomidine is known to provide
renoprotection against ischemia and reperfusion (I/R) injury. However the underlying …

Growing and consistent preclinical evidence, combined with early clinical epidemiological
observations, suggest potentially neurotoxic effects of commonly used anesthetic agents in …

Prolonged exposure to volatile anesthetics, such as isoflurane and sevoflurane, causes
neurodegeneration in the developing animal brains. Recent studies showed that …

Traumatic brain injury (TBI) is one of the most frequent causes of death in the young
population. Several clinical trials have unsuccessfully focused on direct neuroprotective …

Dexmedetomidine (DEX) is a highly selective α2 receptor agonist that is routinely used in
the clinic for sedation and anesthesia. Recently, an increasing number of studies have …