The multiscale physics of cilia and flagella

W Gilpin, MS Bull, M Prakash - Nature Reviews Physics, 2020 - nature.com
Cilia and flagella are fundamental units of motion in cellular biology. These beating, hair-like
organelles share a common basic structure but maintain widely varying functions in systems …

Fluid-structure interaction of bio-inspired flexible slender structures: A review of selected topics

C Wang, H Tang, X Zhang - Bioinspiration & biomimetics, 2022 - iopscience.iop.org
Flexible slender structures are ubiquitous in biological systems and engineering
applications. Fluid-structure interaction (FSI) plays a key role in the dynamics of such …

Miniaturized metachronal magnetic artificial cilia

Z Cui, Y Wang, S Zhang, T Wang… - Proceedings of the …, 2023 - National Acad Sciences
Biological cilia, hairlike organelles on cell surfaces, often exhibit collective wavelike motion
known as metachrony, which helps generating fluid flow. Inspired by nature, researchers …

Rheological analysis of sputum from patients with chronic bronchial diseases

J Patarin, É Ghiringhelli, G Darsy, M Obamba… - Scientific reports, 2020 - nature.com
Bronchial diseases are characterised by the weak efficiency of mucus transport through the
lower airways, leading in some cases to the muco-obstruction of bronchi. It has been …

Microfluidic pumping using artificial magnetic cilia

S Hanasoge, PJ Hesketh, A Alexeev - Microsystems & …, 2018 - nature.com
One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use
spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding …

[HTML][HTML] Mechanisms and functions of multiciliary coordination

KY Wan, RN Poon - Current Opinion in Cell Biology, 2024 - Elsevier
Ciliated organisms are present in virtually every branch of the eukaryotic tree of life. In
diverse systems, cilia operate in a coordinated manner to drive fluid flows, or even propel …

Transport and mixing by metachronal waves in nonreciprocal soft robotic pneumatic artificial cilia at low Reynolds numbers

R Zhang, J den Toonder, PR Onck - Physics of Fluids, 2021 - pubs.aip.org
Cilia are widely employed by living systems to manipulate fluid flow in various functions,
such as feeding, pumping, and locomotion. Mimicking the intricate ciliary asymmetry in …

Active mucus–cilia hydrodynamic coupling drives self-organization of human bronchial epithelium

E Loiseau, S Gsell, A Nommick, C Jomard, D Gras… - Nature Physics, 2020 - nature.com
The respiratory tract is protected by mucus, a complex fluid transported along the epithelial
surface by the coordinated beating of millions of microscopic cilia, hence the name of …

Solid wall and open boundary conditions in hybrid recursive regularized lattice Boltzmann method for compressible flows

Y Feng, S Guo, J Jacob, P Sagaut - Physics of Fluids, 2019 - pubs.aip.org
Complex geometries and open boundaries have been intensively studied in the nearly
incompressible lattice Boltzmann method (LBM) framework. Therefore, only few boundary …

Goblet cell interactions reorient bundled mucus strands for efficient airway clearance

MF Bos, A Ermund, GC Hansson, J de Graaf - PNAS nexus, 2023 - academic.oup.com
The respiratory tract of larger animals is cleared by sweeping bundled strands along the
airway surface. These bundled strands can be millimetric in length and consist of MUC5B …