Autophagy is a well-known cell-survival strategy orchestrated by a conserved set of proteins.
It equips the cells with mechanisms to attain homeostasis during unfavorable conditions …

Abstract In 2011, CAMKK2, the gene encoding calcium/calmodulin-dependent kinase
kinase 2 (CAMKK2), was demonstrated to be a direct target of the androgen receptor and a …

Neural stem cells (NSCs) in the subventricular zone (SVZ) located along the lateral
ventricles (LVs) of the mammalian brain continue to self-renew to produce new neurons after …

Abstract Ethnopharmacological relevance Qian Yang Yu Yin granules (QYYYG) have a long
history in the treatment of hypertensive renal damage (HRD) in China. Clinical studies have …

Although CAMKK2 is overexpressed in several cancers, its role and relevant downstream
signaling pathways in gastric cancer (GC) are poorly understood. Treatment of AGS GC cells …

It is now widely recognized that Ca2+ represents an important and universal second
messenger responsible for the regulation of various cellular processes such as proliferation …

Abstract Background The Ca2+/calmodulin-dependent protein kinase kinases (CaMKKs)
are serine/threonine-directed protein kinases that are activated following increases in …

Background To study the protective effects of delayed remote ischemic preconditioning
(RIPC) against spinal cord ischemia–reperfusion injury (SCIRI) in mice and determine …

Hypothalamic circuits compute systemic information to control metabolism. Astrocytes
residing within the hypothalamus directly sense nutrients and hormones, integrating …

The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2
(CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only …