The power of episodic memories is that they bring a past moment into the present, providing
opportunities for us to recall details of the experiences, reframe or update the memory, and …

Most currently available antidepressants target monoamine neurotransmitter function.
However, a purely neurotransmitter-based explanation for antidepressant drug action is …

The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …

We highlight the role of neuroticism in the development and course of emotional disorders
and make a case for shifting the focus of intervention to this higher-order dimension of …

Rapidly emerging evidence continues to describe an intimate and causal relationship
between sleep and emotional brain function. These findings are mirrored by long-standing …

We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

Background: Psilocybin has shown promise as a treatment for depression but its therapeutic
mechanisms are not properly understood. In contrast to the presumed actions of …

Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …

In this review paper a modified cognitive neurophysiological model of Aaron T. Beck's
cognitive formulation of anxiety and depression is proposed that provides an elaborated …

Cognitive abnormalities are a core feature of depression, and biases toward negatively
toned emotional information are common, but are they a cause or a consequence of …