Background Anastomotic leak rates have not improved over several decades despite
improvements in surgical techniques and patient care. The gut microbiome has been …

We developed a novel clamping device for laparoscopic surgery, free from conventional
pinch structure, capable of uniformly occluding any ductal organ. This study aimed to …

Background Conventional manual compression relies on the surgeon's subjective
sensations, so excessive compression can cause tissue injury to the stapling line of the …

The proper regeneration of vessel anastomoses in microvascular surgery is crucial for
surgical safety. Pituitary adenylate cyclase-activating polypeptide (PACAP) can aid healing …

Introduction Genistein is a natural isoflavonoid and has several pharmacological effects,
such as antioxidant, antitumor activity, and improvement of glucose metabolism. The safety …

Optimizing the regeneration process of surgically created anastomoses (blood vessels,
intestines, nerves) is an important topic in surgical research. One of the most interesting …

Background The effect of remote pre-and postconditioning on anastomotic healing has been
sparsely studied. The aim of our study was to investigate whether remote ischemic …

Purpose Rectal anastomoses have a persisting high incidence of anastomotic leakage. This
study aimed to assess whether the use of a poly-ϵ-caprolactone (PCL) scaffold as …

Objective Anastomotic leakage is a severe complication with multifactorial aetiology,
including impaired tissue oxygenation, infection, inflammation, and anastomotic tension …

The prognosis of colorectal cancer patients with peritoneal metastases is very poor.
Intraperitoneal drug delivery systems, like supramolecular hydrogels, are being developed …