The significant role of microRNAs in gliomas angiogenesis: a particular focus on molecular mechanisms and opportunities for clinical application

A Mafi, R Mannani, S Khalilollah, N Hedayati… - Cellular and Molecular …, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

Circulating RNAs as potential biomarkers in amyotrophic lateral sclerosis

M Ravnik-Glavač, D Glavač - International journal of molecular sciences, 2020 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a complex multi-system neurodegenerative disorder
with currently limited diagnostic and no therapeutic options. Despite the intense efforts no …

Small differences and big changes: the many variables of MicroRNA expression and function in the brain

EV Parkins, C Gross - Journal of Neuroscience, 2024 - jneurosci.org
MicroRNAs are emerging as crucial regulators within the complex, dynamic environment of
the synapse, and they offer a promising new avenue for the treatment of neurological …

[HTML][HTML] Glioblastoma and miRNAs

SP Ahmed, JS Castresana, MH Shahi - Cancers, 2021 - mdpi.com
Glioblastoma (GB) is one of the most common types of lethal brain tumors. Although several
treatment options are available including surgery, along with adjuvant chemo and …

miRNA signature in glioblastoma: Potential biomarkers and therapeutic targets

O Rezaei, K Honarmand, S Nateghinia, M Taheri… - Experimental and …, 2020 - Elsevier
MicroRNAs (miRNAs) are transcripts with sizes of about 22 nucleotides, which are produced
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …

Transcription factor NFAT5 promotes glioblastoma cell-driven angiogenesis via SBF2-AS1/miR-338-3p-mediated EGFL7 expression change

H Yu, J Zheng, X Liu, Y Xue, S Shen, L Zhao… - Frontiers in molecular …, 2017 - frontiersin.org
Glioblastoma (GBM) is the most aggressive primary intracranial tumor of adults and confers
a poor prognosis due to high vascularization. Hence anti-angiogenic therapy has become a …

CircZNF609 promotes cell proliferation, migration, invasion, and glycolysis in nasopharyngeal carcinoma through regulating HRAS via miR-338-3p

Z Liu, F Liu, F Wang, X Yang, W Guo - Molecular and Cellular …, 2021 - Springer
Circular RNA zinc finger protein 609 (circZNF609) has been reported to involve in
nasopharyngeal carcinoma (NPC) tumorigenesis regulation. However, the role and the …

Brain injury and neural stem cells

PE Ludwig, FG Thankam, AA Patil… - Neural regeneration …, 2018 - journals.lww.com
Many therapies with potential for treatment of brain injury have been investigated. Few types
of cells have spurred as much interest and excitement as stem cells over the past few …

miR-142-3p expression is predictive for severe Traumatic Brain Injury (TBI) in trauma patients

CR Schindler, M Woschek, JT Vollrath… - International journal of …, 2020 - mdpi.com
Background: Predictive biomarkers in biofluids are the most commonly used diagnostic
method, but established markers in trauma diagnostics lack accuracy. This study …

[HTML][HTML] Effective biomarkers and therapeutic targets of nerve-immunity interaction in the treatment of depression: an integrated investigation of the miRNA-mRNA …

Z Wu, Z Cai, H Shi, X Huang, M Cai, K Yuan… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Background: Major depressive disorder (MDD) is an emotional condition that interferes with
sufferers' work and daily life. Numerous studies have found that miRNAs play a significant …