Insights into the Mechanism of Low-Valent Cobalt-Catalyzed C–H Activation

JCA Oliveira, U Dhawa, L Ackermann - ACS Catalysis, 2021 - ACS Publications
The use of cobalt complexes of N-heterocycle carbene (NHC) ligands as catalysts for C–H
activation is extremely advantageous due to their low costs and high efficiencies at room …

Salicylaldehyde-Promoted Cobalt-Catalyzed C–H/N–H Annulation of Indolyl Amides with Alkynes: Direct Synthesis of a 5-HT3 Receptor Antagonist Analogue

MG Huang, S Shi, M Li, YJ Liu, MH Zeng - Organic Letters, 2021 - ACS Publications
A cobalt-catalyzed annulation of the C (sp2)–H/N–H bond of indoloamides with alkynes
assisted by 8-aminoquinoline is reported for the synthesis of six-membered indololactams …

Breaking the Monotony: Cobalt and Maleimide as an Entrant to the Olefin-Mediated Ortho C–H Functionalization

T Nanda, SK Banjare, WY Kong, W Guo, P Biswal… - ACS …, 2022 - ACS Publications
A catalytic system is discovered for the intramolecular C–H amidation of N-phenoxy
acetamide derivatives. Herein, a cobalt catalyst has been employed for the olefin-mediated …

Cobalt‐Catalyzed Enantio‐ and Regioselective C(sp3)−H Alkenylation of Thioamides

L Staronova, K Yamazaki, X Xu, H Shi… - Angewandte Chemie …, 2024 - Wiley Online Library
An enantioselective cobalt‐catalyzed C (sp3)− H alkenylation of thioamides with but‐2‐
ynoate ester coupling partners employing thioamide directing groups is presented. The …

Cobalt-Catalyzed C–H Iodination of Aromatic Amides with Molecular Iodine through the Use of a 2-Aminophenyloxazoline-Based Bidentate-Chelation System

Y Kommagalla, N Chatani - Organic letters, 2019 - ACS Publications
The cobalt-catalyzed chelation-assisted C–H iodination of aromatic amides using molecular
iodine as an iodinating reagent is reported. The reaction is carried out in an atmosphere of …

Cobalt/Salicylaldehyde-Enabled C–H Alkoxylation of Benzamides with Secondary Alcohols under Solvothermal Conditions

XH Chen, YQ Xu, MG Huang, ZB Dong… - The Journal of …, 2024 - ACS Publications
C–O bond formation via C–H alkoxylation remains a challenge, especially coupling with a
secondary alcohol, due to its low activity and sterically encumbered property. Here, we …

Mechanistic details of the cobalt-mediated dehydrogenative dimerization of aminoquinoline-directed benzamides

LP Xu, EELN Liu, J Bacsa, CE MacBeth… - Chemical Science, 2020 - pubs.rsc.org
Key mechanistic features of the cobalt-mediated and aminoquinoline-directed
dehydrogenative aryl–aryl coupling were investigated computationally and experimentally …

Electrophilic aromatic substitution

GW Weaver - Organic Reaction Mechanisms 2019: An annual …, 2023 - Wiley Online Library
The significance of aromatic and heterocyclic compounds in both industry and academia
ensures that investigations into new methods of electrophilic aromatic substitution (EAS) and …

[PDF][PDF] Merging Electrosynthesis with 3d Transition Metal-Catalyzed C–H Transformations

TH Meyer - 2021 - d-nb.info
Almost two centuries after Wöhler's fundamental work in organic synthesis,[2] the discipline
has propelled to a central position in molecular assembly of various compounds with …

Oxidation and Reduction

RN Mehrotra - Organic Reaction Mechanisms· 2017: An annual …, 2020 - Wiley Online Library
Summary This Chapter Contains Sections titled: Reviews, Accounts, and Highlights
Oxidation and Reduction by Metal Ions and Related Species Chromium, Manganese, and …