Branched‐chain amino acids (BCAAs) appear to influence several synthetic and catabolic
cellular signaling cascades leading to altered phenotypes in mammals. BCAAs are most …

Branched chain amino acids (BCAA) and their derivatives are bioactive molecules with
pleiotropic functions in the human body. Elevated fasting blood BCAA concentrations are …

Pancreatic ductal adenocarcinoma (PDAC) is an uncommon but highly fatal malignancy.
Identifying causal metabolite biomarkers offers an opportunity to facilitate effective risk …

Fenugreek (Trigonella foenum‐graecum) is a widely grown dietary herb in Asia, and its
seeds are traditionally used for several diseases, including diabetes. The seeds and leaves …

Theaflavins, the characteristic and bioactive polyphenols in black tea, possess the potential
improving effects on insulin resistance-associated metabolic abnormalities, including …

Spices possess tremendous therapeutic potential including hypoglycemic action, attributed
to their bioactive ingredients. However, there is no study that critically reviewed the …

In obesity, macrophages and other immune cells accumulate in organs affected by insulin,
leading to chronic inflammation and insulin resistance. 4-Hydroxyisoleucine (4-HIL) is a non …

Dendritic cell (DCs) activation by Toll-like receptor (TLR) agonist induces robust metabolic
rewiring toward glycolysis. Recent findings in the field identified mechanistic details …

The treatment of obstructive sleep apnea–hypopnea syndrome targets the narrow anatomic
structure of the upper airway (UA) and lacks an effective therapy for UA dilator muscle …

Background Hyperglycemia induced diabetic complications as well as dysfunction of
multiple organs is closely related to the increased inflammation and oxidative stress (OS). 4 …